Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   EL081_RS04030 Genome accession   NZ_LR134266
Coordinates   751272..751946 (+) Length   224 a.a.
NCBI ID   WP_006596563.1    Uniprot ID   -
Organism   Streptococcus viridans strain NCTC3166     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 746272..756946
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL081_RS04010 (NCTC3166_00806) phoU 746427..747080 (+) 654 WP_126404058.1 phosphate signaling complex protein PhoU -
  EL081_RS04015 (NCTC3166_00807) - 747211..749754 (+) 2544 WP_126404059.1 M1 family metallopeptidase -
  EL081_RS04020 (NCTC3166_00808) - 749810..750352 (-) 543 WP_126404060.1 biotin transporter BioY -
  EL081_RS04025 (NCTC3166_00809) - 750562..751158 (+) 597 WP_126404061.1 hypothetical protein -
  EL081_RS04030 (NCTC3166_00810) ciaR 751272..751946 (+) 675 WP_006596563.1 response regulator transcription factor Regulator
  EL081_RS04035 (NCTC3166_00811) ciaH 751936..753309 (+) 1374 WP_126404062.1 HAMP domain-containing sensor histidine kinase Regulator
  EL081_RS04045 (NCTC3166_00812) - 753557..753943 (+) 387 WP_126404063.1 VOC family protein -
  EL081_RS04050 (NCTC3166_00813) - 754139..755524 (+) 1386 WP_126404064.1 polysaccharide deacetylase family protein -
  EL081_RS04055 (NCTC3166_00814) - 755833..756921 (-) 1089 WP_164555431.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25324.05 Da        Isoelectric Point: 4.3320

>NTDB_id=1119574 EL081_RS04030 WP_006596563.1 751272..751946(+) (ciaR) [Streptococcus viridans strain NCTC3166]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKELRDKGVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKVNENTLSYGNVTVNLSTNSTLVEGKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFAKNLQTLRSVGYILKDAQ

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1119574 EL081_RS04030 WP_006596563.1 751272..751946(+) (ciaR) [Streptococcus viridans strain NCTC3166]
ATGATTAAGATTTTATTAGTCGAAGACGACCTTGGTTTGTCTAATTCAGTTTTTGATTTTTTAGATGATTTTGCGGATGT
CATGCAAGTCTTTGATGGGGATGAAGGTCTGTATGAGGCTGAAAGTGGCATCTATGACCTCATTTTGCTAGACCTCATGC
TTCCTGAAAAAGATGGTTTCCAAGTTCTGAAAGAATTGAGAGATAAGGGTGTCTCCACTCCAGTATTGATTATGACAGCC
AAAGAGAGCTTAGACGATAAGGGCCATGGTTTTGAGCTAGGTGCAGATGATTATCTGACCAAGCCATTCTACTTAGAAGA
ACTCAAGATGCGAATCCAAGCATTGTTGAAGCGCTCTGGTAAGGTCAATGAAAATACCCTTTCGTATGGGAATGTGACCG
TTAATCTCTCGACTAACTCTACGCTTGTTGAAGGAAAAGAAGTAGAACTATTAGGAAAAGAATTTGATCTCTTGGTCTAT
TTCCTTCAAAATCAAAATGTTATCCTGCCAAAAACACAAATCTTTGATCGACTTTGGGGATTCGATAGTGATACAACCAT
TTCGGTTGTCGAAGTGTATGTTTCTAAGATTCGTAAGAAGTTAAAAGGAACAGACTTTGCAAAAAATCTCCAAACATTGC
GTAGCGTGGGGTACATTCTGAAAGATGCTCAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

90.625

100

0.906
  ciaR Streptococcus pneumoniae D39

90.625

100

0.906
  ciaR Streptococcus pneumoniae R6

90.625

100

0.906
  ciaR Streptococcus pneumoniae TIGR4

90.625

100

0.906
  ciaR Streptococcus mutans UA159

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.428

100

0.393
  vicR Streptococcus mutans UA159

35.622

100

0.371
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.362

Multiple sequence alignment