Detailed information NTG1119498

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EL071_RS03510
• Genome accession: NZ_LR134265
• Coordinates: 675365..676594 (+)
• Length: 409 a.a.
• NCBI ID: WP_017649189.1
• Uniprot ID: A0AB38VMM8
• Organism: Streptococcus agalactiae strain NCTC8184
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 670365..681594

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL071_RS03485 (NCTC8184_00675)	-	671526..674105 (+)	2580	WP_115357012.1	YfhO family protein	-
EL071_RS03505 (NCTC8184_00679)	rlmH	674685..675164 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EL071_RS03510 (NCTC8184_00680)	htrA	675365..676594 (+)	1230	WP_017649189.1	trypsin-like peptidase domain-containing protein	Regulator
EL071_RS03515 (NCTC8184_00681)	spo0J	676692..677465 (+)	774	WP_000456086.1	ParB/RepB/Spo0J family partition protein	Regulator
EL071_RS03520 (NCTC8184_00682)	dnaA	677674..679035 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
EL071_RS03525 (NCTC8184_00683)	dnaN	679190..680326 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
EL071_RS03530 (NCTC8184_00684)	-	680384..681277 (+)	894	WP_000987442.1	diacylglycerol kinase family protein	-
EL071_RS03535 (NCTC8184_00685)	-	681287..681484 (+)	198	WP_000285197.1	DUF951 family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43063.51 Da
• Isoelectric Point: 9.5271

>NTDB_id=1119498 EL071_RS03510 WP_017649189.1 675365..676594(+) (htrA) [Streptococcus agalactiae strain NCTC8184]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGSSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=1119498 EL071_RS03510 WP_017649189.1 675365..676594(+) (htrA) [Streptococcus agalactiae strain NCTC8184]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAAGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACGGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAGTAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCACCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (300-395)

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.359	96.088	0.609
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.533	97.311	0.55
htrA	Streptococcus pneumoniae TIGR4	55.037	99.511	0.548
htrA	Streptococcus pneumoniae Rx1	55.037	99.511	0.548
htrA	Streptococcus pneumoniae D39	55.037	99.511	0.548
htrA	Streptococcus pneumoniae R6	55.037	99.511	0.548