Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   EL020_RS08475 Genome accession   NZ_LR134203
Coordinates   1664263..1666176 (-) Length   637 a.a.
NCBI ID   WP_126402640.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC11436     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1659263..1671176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL020_RS08450 (NCTC11436_01807) - 1659937..1660293 (-) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  EL020_RS10010 (NCTC11436_01808) - 1660293..1661693 (-) 1401 WP_081048448.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL020_RS08460 (NCTC11436_01809) - 1661817..1662461 (-) 645 WP_020916314.1 response regulator -
  EL020_RS08465 (NCTC11436_01810) - 1662445..1663470 (-) 1026 WP_020916313.1 sensor histidine kinase -
  EL020_RS08470 (NCTC11436_01811) liaF 1663467..1664162 (-) 696 WP_058813684.1 cell wall-active antibiotics response protein LiaF -
  EL020_RS08475 (NCTC11436_01812) stkP/pknB 1664263..1666176 (-) 1914 WP_126402640.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL020_RS08480 (NCTC11436_01813) - 1666176..1666913 (-) 738 WP_043894973.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL020_RS08485 (NCTC11436_01814) rsmB 1666951..1668273 (-) 1323 WP_020916309.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL020_RS08490 (NCTC11436_01815) fmt 1668263..1669198 (-) 936 WP_020916308.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69083.95 Da        Isoelectric Point: 6.4499

>NTDB_id=1118983 EL020_RS08475 WP_126402640.1 1664263..1666176(-) (stkP/pknB) [Streptococcus lutetiensis strain NCTC11436]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTTEQLLTKQKAAKVN
REAADNKIAKAKTKKKKSHHMFGTLVKIFFAVVVVAIAIFTYLTLSTPASVNVPDVAGTSLQAAKTSLTSAGLKVGRTKG
IYSDTVPSGQVIETNPKAGTSKKEGAKVDIYVSKGTSGFKMKDYTGQNYQEVIKELKDKHGISSDKIDVEWITGTNYDGG
TIISQTPEKGTKVASEDKITFKVAAIVMPNLIGYTYQDAIAELTALGLSSSHIIVFQADATSSTGYSQVKTPSASAIVVA
QDPYFGVSIEGEVNLYFSARSEAQSSEVAPSQSVSESYETSETSESSSLSSSSSSSSSSSSSSSTEESSQTDSSSVE

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=1118983 EL020_RS08475 WP_126402640.1 1664263..1666176(-) (stkP/pknB) [Streptococcus lutetiensis strain NCTC11436]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAGTCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATCTAATTCTTGATAATGAAGAAGTGGCTATCAAAGTCCTTCGAACTAATTATCAAACAGATCAAATTG
CCGTTGCTCGTTTCCAACGTGAAGCACGTGCCATGGCAGAGCTAAACCATCCAAATATCGTTTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTGAAAAAATATATTCAAGACCACGCCCC
TCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTGTCTGCGATGACTTTGGCTCATCAACAAGGAATTGTTC
ACCGTGATTTGAAACCACAAAATATCTTGTTAACCAAAGACGGAACGGTTAAAGTTACCGACTTTGGTATCGCTGTAGCT
TTTGCAGAAACAAGTTTAACACAAACAAACTCAATGCTTGGTAGTGTACACTATTTATCACCTGAACAAGCGCGTGGTTC
AAAAGCCACTGTTCAAAGTGATATCTACGCTATGGGGATTATGTTGTTTGAAATGTTGACTGGTCACATTCCATATGATG
GTGATTCAGCTGTTACGATTGCTCTTCAACATTTCCAAAAACCACTTCCATCAATCATTGATGAAAATAAAAATGTTCCA
CAAGCTTTGGAAAATGTTGTCATTAAAGCAACTGCAAAACGTTTGAGTGATCGCTACGCCTCAACTTTTGAAATGAGTCG
TGATTTAATGACTGCTCTCTCATATAACCGTAGCCGCGAACGCAAACTTGTCTTTGAAGATACAGAAAATACGAAGACAC
TTCCAAAAGTAACAACTTCAACACCTGTTCCCTCAACAACAGAACAATTGTTGACAAAACAAAAAGCAGCTAAAGTTAAT
CGTGAAGCTGCGGATAATAAAATTGCAAAAGCGAAAACGAAGAAGAAAAAATCACATCATATGTTTGGTACTTTAGTGAA
AATTTTCTTTGCGGTCGTAGTAGTTGCAATTGCTATCTTTACTTACTTGACGCTAAGCACACCAGCTTCAGTCAACGTTC
CAGATGTAGCTGGAACAAGTTTACAAGCTGCTAAGACAAGTCTTACATCAGCAGGACTTAAAGTTGGAAGGACCAAGGGA
ATTTATAGTGATACTGTTCCAAGTGGTCAGGTTATTGAGACTAATCCGAAAGCTGGCACATCTAAGAAAGAAGGTGCCAA
AGTTGACATTTATGTGTCAAAAGGAACATCAGGCTTTAAGATGAAAGATTATACTGGTCAAAACTATCAAGAAGTTATCA
AAGAACTCAAAGATAAACACGGTATTTCAAGTGATAAGATTGATGTTGAATGGATAACAGGCACTAACTATGATGGTGGT
ACTATCATTAGTCAAACACCTGAAAAAGGTACAAAAGTTGCTAGTGAAGATAAGATTACTTTCAAGGTTGCAGCAATCGT
TATGCCAAACCTTATTGGTTATACTTATCAAGATGCAATTGCTGAATTGACTGCACTTGGCTTATCAAGTTCGCATATTA
TAGTATTCCAAGCAGATGCTACTTCATCAACTGGATATTCTCAAGTTAAAACACCATCTGCCTCTGCAATTGTTGTGGCA
CAAGATCCTTACTTTGGCGTATCTATTGAAGGAGAGGTTAACCTTTACTTCTCAGCTAGAAGTGAAGCTCAGTCTTCAGA
AGTTGCACCATCTCAATCTGTTTCTGAGTCATATGAGACAAGTGAAACTAGTGAGTCAAGTTCTTTAAGTAGCAGCAGTA
GCAGCAGTAGTAGCAGCAGTAGCAGTAGCAGCACTGAAGAAAGTTCACAAACCGACTCATCATCAGTTGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-578)

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-503)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

59.843

99.686

0.597
  pknB Streptococcus mutans UA159

65.505

90.11

0.59
  stkP Streptococcus pneumoniae TIGR4

58.569

83.359

0.488
  stkP Streptococcus pneumoniae D39

58.38

83.359

0.487
  stkP Streptococcus pneumoniae R6

58.38

83.359

0.487
  stkP Streptococcus pneumoniae Rx1

58.192

83.359

0.485

Multiple sequence alignment