Detailed information NTG1118940

Bioinformatically predicted

Overview

• Name: comD/comD2
• Type: Regulator
• Locus tag: EL020_RS02020
• Genome accession: NZ_LR134203
• Coordinates: 397305..398138 (-)
• Length: 277 a.a.
• NCBI ID: WP_126402358.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC11436
• Function: phosphorylation of ComE (predicted from homology) Competence regulation

Genomic Context

Location: 392305..403138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL020_RS01995 (NCTC11436_00415)	-	393530..394162 (-)	633	WP_020917486.1	thiamine diphosphokinase	-
EL020_RS02000 (NCTC11436_00416)	rpe	394155..394817 (-)	663	WP_020917487.1	ribulose-phosphate 3-epimerase	-
EL020_RS02005 (NCTC11436_00417)	rsgA	394824..395696 (-)	873	WP_058814253.1	ribosome small subunit-dependent GTPase A	-
EL020_RS09710 (NCTC11436_00419)	comE/comE2	396014..396466 (-)	453	WP_231997006.1	LytR/AlgR family response regulator transcription factor	Regulator
EL020_RS09715 (NCTC11436_00420)	comE/comE2	396520..396747 (-)	228	WP_228380495.1	hypothetical protein	Regulator
EL020_RS02020 (NCTC11436_00421)	comD/comD2	397305..398138 (-)	834	WP_126402358.1	sensor histidine kinase	Regulator
EL020_RS02025 (NCTC11436_00422)	-	399033..399326 (-)	294	WP_126402359.1	bacteriocin immunity protein	-
EL020_RS02030 (NCTC11436_00423)	-	399354..399659 (-)	306	WP_058832827.1	bacteriocin immunity protein	-
EL020_RS02035	-	399672..399821 (-)	150	WP_020917491.1	hypothetical protein	-
EL020_RS02040 (NCTC11436_00424)	rsmA	400228..401100 (-)	873	WP_004233302.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
EL020_RS02045 (NCTC11436_00425)	rnmV	401223..401792 (-)	570	WP_043895125.1	ribonuclease M5	-
EL020_RS02050 (NCTC11436_00426)	-	401785..402555 (-)	771	WP_003066600.1	TatD family hydrolase	-
EL020_RS09720	-	402692..402769 (-)	78	WP_230318136.1	hypothetical protein	-
EL020_RS09725	-	402970..403083 (-)	114	WP_231557400.1	Cna B-type domain-containing protein	-

Sequence

Protein

• Length: 277 a.a.
• Molecular weight: 31741.14 Da
• Isoelectric Point: 4.6102

>NTDB_id=1118940 EL020_RS02020 WP_126402358.1 397305..398138(-) (comD/comD2) [Streptococcus lutetiensis strain NCTC11436]
MVSYFLFMDAVAIVKSFHNTVNDAIRGIVAFIYLILLFAFLFYLNFRHGQEQKNELLRNQEMELAALENYSKHVESLYQE
VRSFRHDYANVLMSLKVGIDQGNLDDIKKIYNEITANSTKLVKNNKFDLTRLANIIDSGVKSFMSAKFLQAENQGIAISL
EVTEKMENPSIPLIYYIRILSILFDNAIEAALESETPEISVANFYQDGNFVFMIENSTKEKSVDLTKIFERGYSTKGENR
GLGLATLMDFQDDDENLSVEIRSSDYTFTQVVRIFDA

Nucleotide

• Length: 834 bp

>NTDB_id=1118940 EL020_RS02020 WP_126402358.1 397305..398138(-) (comD/comD2) [Streptococcus lutetiensis strain NCTC11436]
ATGGTCTCTTATTTTTTATTCATGGATGCCGTTGCTATTGTAAAATCTTTTCATAATACTGTTAACGATGCAATAAGGGG
AATTGTTGCTTTCATTTATCTCATCCTTCTTTTTGCCTTCCTCTTTTATCTTAATTTCCGTCATGGGCAAGAGCAGAAAA
ATGAATTGCTTCGTAACCAGGAAATGGAATTGGCGGCCTTGGAAAATTATAGCAAGCACGTGGAGAGTTTGTATCAGGAG
GTTCGCAGTTTCAGGCATGACTACGCTAATGTCCTGATGAGTTTAAAGGTTGGAATTGATCAAGGCAATCTTGATGACAT
CAAGAAAATTTACAACGAAATCACAGCCAATTCGACGAAGCTAGTCAAGAATAATAAATTTGACCTGACTCGCTTGGCTA
ACATCATAGACAGCGGCGTCAAAAGCTTCATGTCAGCTAAATTTTTGCAAGCCGAAAATCAAGGGATTGCAATTAGTCTA
GAAGTCACCGAAAAAATGGAAAATCCTAGCATTCCATTAATTTATTACATTCGAATTTTGTCGATTCTGTTTGATAATGC
CATAGAAGCCGCTTTGGAGTCAGAAACTCCAGAAATCTCAGTCGCTAATTTTTACCAAGATGGTAACTTTGTTTTCATGA
TTGAGAATTCAACTAAGGAAAAATCAGTGGATTTAACTAAGATTTTTGAGCGTGGCTACTCAACTAAGGGAGAAAATCGT
GGACTTGGTCTAGCCACACTAATGGATTTCCAAGATGACGACGAAAATCTGTCAGTTGAAATTCGCAGCTCAGATTACAC
ATTTACACAAGTTGTCCGAATTTTTGATGCATAA

Domains

Predicted by InterproScan.

• GHKL domain (HATPase_c_5) (177-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/comD2	Streptococcus equinus JB1	88.087	100	0.881
comD/comD3	Streptococcus equinus JB1	83.026	97.834	0.812
comD/comD1	Streptococcus equinus JB1	47.186	83.394	0.394
comD/blpH	Streptococcus mutans UA159	39.416	98.917	0.39