Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ELZ63_RS01370 Genome accession   NZ_LR134171
Coordinates   272232..273569 (+) Length   445 a.a.
NCBI ID   WP_065245038.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC12699     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 267232..278569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ63_RS01345 (NCTC12699_00265) - 267297..269891 (-) 2595 WP_065245042.1 penicillin-binding protein 1A -
  ELZ63_RS01350 (NCTC12699_00266) comA 269990..270787 (+) 798 WP_065245041.1 competence protein ComA Machinery gene
  ELZ63_RS01355 (NCTC12699_00267) comB 270788..271294 (+) 507 WP_005652121.1 competence protein ComB Machinery gene
  ELZ63_RS01360 (NCTC12699_00268) comC 271291..271812 (+) 522 WP_065245040.1 competence protein ComC Machinery gene
  ELZ63_RS01365 (NCTC12699_00269) comD 271809..272222 (+) 414 WP_065245039.1 pilus assembly protein PilP Machinery gene
  ELZ63_RS01370 (NCTC12699_00270) comE 272232..273569 (+) 1338 WP_065245038.1 type IV pilus secretin PilQ family protein Machinery gene
  ELZ63_RS01375 (NCTC12699_00271) - 273582..274268 (+) 687 WP_065245037.1 ComF family protein -
  ELZ63_RS01380 (NCTC12699_00272) nfuA 274344..274940 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  ELZ63_RS01385 (NCTC12699_00273) nudC 275007..275801 (+) 795 WP_014550416.1 NAD(+) diphosphatase -
  ELZ63_RS01390 (NCTC12699_00274) - 275837..276427 (+) 591 WP_048954881.1 YjaG family protein -
  ELZ63_RS01395 (NCTC12699_00275) - 276567..276839 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49244.58 Da        Isoelectric Point: 8.2628

>NTDB_id=1118729 ELZ63_RS01370 WP_065245038.1 272232..273569(+) (comE) [Haemophilus influenzae strain NCTC12699]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPVGSITFDDRSN
LLVIQDEPRFVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVSYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PIIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=1118729 ELZ63_RS01370 WP_065245038.1 272232..273569(+) (comE) [Haemophilus influenzae strain NCTC12699]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCCCAAACACTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGGTTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAGGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGTGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCTGTGGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTTTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCAAGCA
TTAAACAGGGGACAGAAATTCCTTACGTCGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTGAGTCAAAATTCCCCTGG
TTCTCGTGTCTCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCATTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGCAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.652

100

0.987
  comE Haemophilus influenzae Rd KW20

97.079

100

0.971
  comE Glaesserella parasuis strain SC1401

51.765

95.506

0.494
  pilQ Vibrio campbellii strain DS40M4

42.959

94.157

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.99

92.584

0.389
  pilQ Vibrio cholerae strain A1552

41.99

92.584

0.389

Multiple sequence alignment