Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   ELZ63_RS01355 Genome accession   NZ_LR134171
Coordinates   270788..271294 (+) Length   168 a.a.
NCBI ID   WP_005652121.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC12699     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 265788..276294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ63_RS01335 (NCTC12699_00263) - 265897..266226 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  ELZ63_RS01340 (NCTC12699_00264) - 266379..267224 (-) 846 WP_005656472.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  ELZ63_RS01345 (NCTC12699_00265) - 267297..269891 (-) 2595 WP_065245042.1 penicillin-binding protein 1A -
  ELZ63_RS01350 (NCTC12699_00266) comA 269990..270787 (+) 798 WP_065245041.1 competence protein ComA Machinery gene
  ELZ63_RS01355 (NCTC12699_00267) comB 270788..271294 (+) 507 WP_005652121.1 competence protein ComB Machinery gene
  ELZ63_RS01360 (NCTC12699_00268) comC 271291..271812 (+) 522 WP_065245040.1 competence protein ComC Machinery gene
  ELZ63_RS01365 (NCTC12699_00269) comD 271809..272222 (+) 414 WP_065245039.1 pilus assembly protein PilP Machinery gene
  ELZ63_RS01370 (NCTC12699_00270) comE 272232..273569 (+) 1338 WP_065245038.1 type IV pilus secretin PilQ family protein Machinery gene
  ELZ63_RS01375 (NCTC12699_00271) - 273582..274268 (+) 687 WP_065245037.1 ComF family protein -
  ELZ63_RS01380 (NCTC12699_00272) nfuA 274344..274940 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  ELZ63_RS01385 (NCTC12699_00273) nudC 275007..275801 (+) 795 WP_014550416.1 NAD(+) diphosphatase -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19653.50 Da        Isoelectric Point: 7.4220

>NTDB_id=1118726 ELZ63_RS01355 WP_005652121.1 270788..271294(+) (comB) [Haemophilus influenzae strain NCTC12699]
MSMNLLPWRTYQHQKRLRRLAFYIALCILLAINLMLAFSNLIEQQKQNLQAQQTSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=1118726 ELZ63_RS01355 WP_005652121.1 270788..271294(+) (comB) [Haemophilus influenzae strain NCTC12699]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATG
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAAGCGCAGCAAA
CATCTTTTGAACAACTTAATCAGCAACTTCACAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGTTTGGAAGGTAACGCGCAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

99.405

100

0.994
  comB Haemophilus influenzae Rd KW20

98.214

100

0.982

Multiple sequence alignment