Detailed information NTG1118307

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: ELZ51_RS11055
• Genome accession: NZ_LR134094
• Coordinates: 2199553..2200773 (+)
• Length: 406 a.a.
• NCBI ID: WP_003048956.1
• Uniprot ID: A0A380JYG2
• Organism: Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2194553..2205773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ51_RS11030 (NCTC4669_02323)	-	2195500..2198106 (+)	2607	WP_126427578.1	YfhO family protein	-
ELZ51_RS11050 (NCTC4669_02327)	rlmH	2198864..2199343 (-)	480	WP_003053217.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
ELZ51_RS11055 (NCTC4669_02328)	htrA	2199553..2200773 (+)	1221	WP_003048956.1	S1C family serine protease	Regulator
ELZ51_RS11060 (NCTC4669_02329)	spo0J	2200888..2201661 (+)	774	WP_115253230.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 406 a.a.
• Molecular weight: 42695.23 Da
• Isoelectric Point: 6.3566

>NTDB_id=1118307 ELZ51_RS11055 WP_003048956.1 2199553..2200773(+) (htrA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MPSMKHILKSLGILLIGFLGGLLAIFTFNATQQSSSTSHTSSATMSKMVFNNTTDTTKAVKVVQNAVVSVINYQADPSSS
LSNPYTKLFGENPAREDKDSELTVFAQGSGVIYRKDSNHAYVVTNNHVIDGAKRIEILMADGTKVVGELIGADTYSDLAV
VKISSDKIKTVAEFADSTKLNVGETAIAIGSPLGTQYANSVTKGIVSSLSRTVTLKNEDGETVSTNAIQTDAAINPGNSG
GPLINIEGQVIGINSSKISSTPSGINGNSGAVEGISFAIPSNDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQI
NIPTSITGGIVVGSVQEGMPASGKLAQYDVITEIDGKAVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKTDITLTKTTQ
DLTKKQ

Nucleotide

• Length: 1221 bp

>NTDB_id=1118307 ELZ51_RS11055 WP_003048956.1 2199553..2200773(+) (htrA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGCCATCTATGAAACATATCTTAAAATCCTTAGGCATTTTACTCATTGGATTTTTAGGAGGATTGTTAGCAATTTTCAC
TTTTAATGCTACTCAACAGTCTTCCTCTACCTCACATACTAGTAGTGCGACGATGAGTAAGATGGTTTTTAATAATACTA
CTGACACAACAAAAGCGGTTAAAGTCGTCCAAAACGCAGTAGTATCAGTGATTAACTATCAAGCAGATCCTTCTTCATCT
CTTTCTAATCCTTACACAAAACTCTTTGGAGAAAATCCAGCAAGAGAAGATAAAGATTCCGAATTAACAGTTTTTGCTCA
AGGTTCTGGTGTCATTTATCGAAAAGATTCCAATCATGCCTATGTTGTGACTAATAATCATGTTATTGACGGCGCAAAAC
GAATTGAAATTCTTATGGCAGATGGAACTAAGGTAGTAGGAGAATTAATTGGTGCGGATACTTATTCTGACTTAGCTGTA
GTTAAAATTTCTTCAGATAAGATTAAAACAGTAGCTGAATTTGCAGATTCTACTAAACTTAATGTTGGAGAAACTGCTAT
TGCTATTGGTAGTCCACTGGGAACTCAATACGCAAACTCAGTTACGAAAGGAATTGTATCGAGCCTAAGTCGTACCGTTA
CCTTAAAAAACGAAGATGGAGAAACTGTTTCAACAAATGCTATCCAAACAGATGCTGCTATTAACCCCGGAAATTCTGGG
GGACCACTAATTAATATAGAAGGACAGGTTATCGGTATTAATTCAAGTAAGATTTCTTCTACTCCATCTGGTATTAATGG
GAATAGTGGAGCTGTCGAAGGAATTAGCTTTGCTATTCCATCTAATGATGTCATTAAAATCATTAAGCAATTAGAAACCA
ACGGTGAAGTCATACGACCTGCTCTTGGTATCTCTATGGTTAACCTAAATGATTTATCAACTAATGCTCTTAGTCAAATT
AATATCCCAACTAGTATCACTGGCGGCATTGTGGTTGGTTCTGTTCAAGAGGGAATGCCAGCAAGTGGTAAACTTGCCCA
GTACGATGTCATTACAGAAATTGATGGGAAAGCTGTTAATTCAATAAGTGATCTTCAAAGTAGTCTATATGGCCATGACA
TTAACGATACCATCAAGGTAACCTTTTATAGAGGGACAACCAAGAAAAAAACAGATATTACCTTAACTAAAACAACTCAG
GATTTGACCAAAAAACAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (300-395)

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

3D structure

• AlphaFold DB: A0A380JYG2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.204	99.015	0.586
htrA	Streptococcus mitis NCTC 12261	54.054	100	0.542
htrA	Streptococcus pneumoniae Rx1	54.054	100	0.542
htrA	Streptococcus pneumoniae TIGR4	54.054	100	0.542
htrA	Streptococcus pneumoniae D39	54.054	100	0.542
htrA	Streptococcus pneumoniae R6	54.054	100	0.542
htrA	Streptococcus gordonii str. Challis substr. CH1	54.208	99.507	0.539