Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ELZ51_RS05930 Genome accession   NZ_LR134094
Coordinates   1149546..1150220 (-) Length   224 a.a.
NCBI ID   WP_003050941.1    Uniprot ID   A0A380JVA5
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1144546..1155220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS05905 (NCTC4669_01244) - 1144731..1146008 (-) 1278 WP_126426620.1 pyrimidine-nucleoside phosphorylase -
  ELZ51_RS05910 (NCTC4669_01245) - 1145995..1146594 (-) 600 WP_037584951.1 class I SAM-dependent methyltransferase -
  ELZ51_RS05915 (NCTC4669_01246) coaA 1146863..1147783 (+) 921 WP_126426622.1 type I pantothenate kinase -
  ELZ51_RS05920 (NCTC4669_01247) rpsT 1147837..1148085 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  ELZ51_RS05925 (NCTC4669_01248) ciaH 1148243..1149553 (-) 1311 WP_115252901.1 sensor histidine kinase Regulator
  ELZ51_RS05930 (NCTC4669_01249) ciaR 1149546..1150220 (-) 675 WP_003050941.1 response regulator transcription factor Regulator
  ELZ51_RS05935 (NCTC4669_01250) - 1150425..1152962 (-) 2538 WP_003050944.1 M1 family metallopeptidase -
  ELZ51_RS05940 (NCTC4669_01251) phoU 1153162..1153815 (-) 654 WP_126426624.1 phosphate signaling complex protein PhoU -
  ELZ51_RS05945 (NCTC4669_01252) pstB 1153893..1154651 (-) 759 WP_003050947.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25539.54 Da        Isoelectric Point: 4.4684

>NTDB_id=1118285 ELZ51_RS05930 WP_003050941.1 1149546..1150220(-) (ciaR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MLKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGKKEVQVDGQPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDLVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1118285 ELZ51_RS05930 WP_003050941.1 1149546..1150220(-) (ciaR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGCTCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGAGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGTTTTCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCAGTGTTGATCATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACGGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAACGTCGTAG
TGGATTTAGGAAAAAAAGAAGTTCAAGTGGATGGCCAACCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTTTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATCTTGTGGACAAACTTCAGACATTAA
GAAGTGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae D39

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae R6

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae TIGR4

83.71

98.661

0.826
  ciaR Streptococcus mutans UA159

83.258

98.661

0.821
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.379
  vicR Streptococcus mutans UA159

35.443

100

0.375

Multiple sequence alignment