Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ELZ51_RS05925 Genome accession   NZ_LR134094
Coordinates   1148243..1149553 (-) Length   436 a.a.
NCBI ID   WP_115252901.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1143243..1154553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS05895 (NCTC4669_01242) - 1143677..1144066 (-) 390 WP_003050928.1 cytidine deaminase -
  ELZ51_RS05900 (NCTC4669_01243) deoC 1144053..1144715 (-) 663 WP_115252900.1 deoxyribose-phosphate aldolase -
  ELZ51_RS05905 (NCTC4669_01244) - 1144731..1146008 (-) 1278 WP_126426620.1 pyrimidine-nucleoside phosphorylase -
  ELZ51_RS05910 (NCTC4669_01245) - 1145995..1146594 (-) 600 WP_037584951.1 class I SAM-dependent methyltransferase -
  ELZ51_RS05915 (NCTC4669_01246) coaA 1146863..1147783 (+) 921 WP_126426622.1 type I pantothenate kinase -
  ELZ51_RS05920 (NCTC4669_01247) rpsT 1147837..1148085 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  ELZ51_RS05925 (NCTC4669_01248) ciaH 1148243..1149553 (-) 1311 WP_115252901.1 sensor histidine kinase Regulator
  ELZ51_RS05930 (NCTC4669_01249) ciaR 1149546..1150220 (-) 675 WP_003050941.1 response regulator transcription factor Regulator
  ELZ51_RS05935 (NCTC4669_01250) - 1150425..1152962 (-) 2538 WP_003050944.1 M1 family metallopeptidase -
  ELZ51_RS05940 (NCTC4669_01251) phoU 1153162..1153815 (-) 654 WP_126426624.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49834.38 Da        Isoelectric Point: 8.2353

>NTDB_id=1118284 ELZ51_RS05925 WP_115252901.1 1148243..1149553(-) (ciaH) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MNKLKKEVLSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLMNFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAVFENYQLVAEENGKVFLFEN
QVNRTLKMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1118284 ELZ51_RS05925 WP_115252901.1 1148243..1149553(-) (ciaH) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGAATAAATTAAAAAAAGAAGTCCTCTCTGATCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCTTCTTTTTACTTTGATGCAGAAAATAATGTTATT
AAACCTTTGCCTGATTCAGACAATTCAAAGTTAGTAGGAACACCGGCGGCAAATACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTTTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACCACTAGCCTGATGAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTTGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATTATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGTCGAAAGCCGATTTTGG
AAAGTTACGAAAAACAAAAAATGTTTGTGGAAAATGCCAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCCCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACACTTGGCTTCGAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGACGATGGGATCAACCCCCAGTGGACTGACCTGG
ACGCTACCTTTTTTGATGCTGTTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCACCTTGAAAATGGACAAGGCTCTTTTGAAGCAATTGATGACGATTTTATTTGATAATGCGATTAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTAGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.352

100

0.585
  ciaH Streptococcus pneumoniae Rx1

51.598

100

0.518
  ciaH Streptococcus pneumoniae D39

51.598

100

0.518
  ciaH Streptococcus pneumoniae R6

51.598

100

0.518
  ciaH Streptococcus pneumoniae TIGR4

51.598

100

0.518

Multiple sequence alignment