Detailed information NTG1116195

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: EQB41_RS06635
• Genome accession: NZ_LR129840
• Coordinates: 1243596..1244444 (-)
• Length: 282 a.a.
• NCBI ID: WP_127820798.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4496 isolate 4496
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1238596..1249444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB41_RS06620	-	1238952..1239311 (-)	360	WP_001237223.1	YbaN family protein	-
EQB41_RS06625	topA	1239417..1241504 (-)	2088	WP_000179644.1	type I DNA topoisomerase	-
EQB41_RS06630	-	1241671..1242714 (-)	1044	WP_127820797.1	TIGR00341 family protein	-
EQB41_RS12630	-	1243291..1243413 (+)	123	WP_001814242.1	hypothetical protein	-
EQB41_RS06635	dprA/cilB/dalA	1243596..1244444 (-)	849	WP_127820798.1	DNA-processing protein DprA	Machinery gene
EQB41_RS06640	-	1244530..1245219 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
EQB41_RS06645	-	1245231..1246109 (-)	879	WP_000837618.1	DMT family transporter	-
EQB41_RS06650	licA	1246099..1246968 (-)	870	WP_000411215.1	choline kinase LicA	-
EQB41_RS06655	-	1246985..1248007 (-)	1023	WP_000609887.1	ribitol-5-phosphate dehydrogenase	-
EQB41_RS06660	-	1248012..1248719 (-)	708	WP_000638527.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31020.64 Da
• Isoelectric Point: 5.4006

>NTDB_id=1116195 EQB41_RS06635 WP_127820798.1 1243596..1244444(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 4496 isolate 4496]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQDLLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=1116195 EQB41_RS06635 WP_127820798.1 1243596..1244444(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGATCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAACAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGCTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.291	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis SK321	97.163	100	0.972
dprA	Streptococcus mutans UA159	63.214	99.291	0.628
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362