Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   EQB41_RS04870 Genome accession   NZ_LR129840
Coordinates   892735..893385 (+) Length   216 a.a.
NCBI ID   WP_127820764.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4496 isolate 4496     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 887735..898385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB41_RS04840 - 888231..888446 (+) 216 WP_001232078.1 YozE family protein -
  EQB41_RS04845 - 888532..889500 (+) 969 WP_000658181.1 PhoH family protein -
  EQB41_RS04850 - 889680..890180 (+) 501 WP_000566988.1 GNAT family N-acetyltransferase -
  EQB41_RS04855 - 890183..890509 (+) 327 Protein_916 TfoX/Sxy family protein -
  EQB41_RS04860 ald 890810..891921 (-) 1112 Protein_917 alanine dehydrogenase -
  EQB41_RS04865 - 892098..892667 (+) 570 WP_000443745.1 GNAT family N-acetyltransferase -
  EQB41_RS04870 comEA/celA/cilE 892735..893385 (+) 651 WP_127820764.1 helix-hairpin-helix domain-containing protein Machinery gene
  EQB41_RS04875 - 893369..895609 (+) 2241 Protein_920 DNA internalization-related competence protein ComEC/Rec2 -
  EQB41_RS04880 - 895789..895977 (+) 189 WP_010976492.1 hypothetical protein -
  EQB41_RS04885 - 896009..896596 (+) 588 WP_000933542.1 ATP-binding cassette domain-containing protein -
  EQB41_RS04890 - 896600..897775 (+) 1176 WP_127820765.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23043.22 Da        Isoelectric Point: 6.0661

>NTDB_id=1116189 EQB41_RS04870 WP_127820764.1 892735..893385(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 4496 isolate 4496]
MEAIIEKIKEYKIIGICTGLGLLVGGFFLLKPAPQTSVKETNLQAEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1116189 EQB41_RS04870 WP_127820764.1 892735..893385(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGGCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACATCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGGAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACCATAGAAAAACTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

97.222

100

0.972
  comEA/celA/cilE Streptococcus pneumoniae Rx1

95.37

100

0.954
  comEA/celA/cilE Streptococcus pneumoniae D39

95.37

100

0.954
  comEA/celA/cilE Streptococcus pneumoniae R6

95.37

100

0.954
  comEA/celA/cilE Streptococcus mitis NCTC 12261

94.907

100

0.949
  comEA/celA/cilE Streptococcus mitis SK321

92.13

100

0.921
  comEA Lactococcus lactis subsp. cremoris KW2

44.053

100

0.463
  comEA Latilactobacillus sakei subsp. sakei 23K

34.335

100

0.37

Multiple sequence alignment