Detailed information NTG1116141

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SP119_RS04795
• Genome accession: NZ_LR031521
• Coordinates: 914409..915245 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain S119 isolate S119
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 909409..920245

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP119_RS04765 (SP119_0885)	-	909963..910331 (+)	369	WP_010922310.1	hypothetical protein	-
SP119_RS04770 (SP119_0886)	-	910381..911292 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
SP119_RS04775 (SP119_0887)	trhA	911409..912059 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
SP119_RS04780 (SP119_0888)	-	912056..912496 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
SP119_RS04785 (SP119_0889)	ylqF	912715..913563 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
SP119_RS04790 (SP119_0890)	-	913553..914344 (+)	792	WP_011285534.1	ribonuclease HII	-
SP119_RS04795 (SP119_0891)	dprA	914409..915245 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
SP119_RS04800 (SP119_0892)	topA	915352..917481 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
SP119_RS09775	-	917556..918438 (-)	883	Protein_873	LysR family transcriptional regulator	-
SP119_RS04815 (SP119_0895)	-	918451..918996 (+)	546	Protein_874	PTS sugar transporter subunit IIC	-
SP119_RS04820 (SP119_0896)	-	919011..920003 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=1116141 SP119_RS04795 WP_010922314.1 914409..915245(+) (dprA) [Streptococcus pyogenes strain S119 isolate S119]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1116141 SP119_RS04795 WP_010922314.1 914409..915245(+) (dprA) [Streptococcus pyogenes strain S119 isolate S119]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367