Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HAS68_RS05945 Genome accession   NZ_CP002007
Coordinates   1169807..1170649 (+) Length   280 a.a.
NCBI ID   WP_009909860.1    Uniprot ID   A0A075SDJ3
Organism   Streptococcus suis 05HAS68     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1164807..1175649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HAS68_RS05915 (HAS68_1078) - 1165530..1166180 (-) 651 WP_002936498.1 hemolysin III family protein -
  HAS68_RS05920 (HAS68_1079) - 1166170..1166721 (-) 552 WP_002936497.1 DUF1836 domain-containing protein -
  HAS68_RS05925 (HAS68_1080) - 1166829..1168481 (-) 1653 WP_002936496.1 FAD-dependent oxidoreductase -
  HAS68_RS05930 (HAS68_1081) - 1168478..1168801 (-) 324 WP_002936495.1 rhodanese-like domain-containing protein -
  HAS68_RS05935 (HAS68_1082) - 1168920..1169180 (+) 261 WP_009909865.1 metal-sensitive transcriptional regulator -
  HAS68_RS05940 (HAS68_1083) - 1169191..1169748 (+) 558 WP_009909862.1 sugar O-acetyltransferase -
  HAS68_RS05945 (HAS68_1084) dprA 1169807..1170649 (+) 843 WP_009909860.1 DNA-processing protein DprA Machinery gene
  HAS68_RS05950 (HAS68_1085) topA 1170742..1172835 (+) 2094 WP_024409355.1 type I DNA topoisomerase -
  HAS68_RS05955 (HAS68_1086) rplJ 1173412..1173906 (+) 495 WP_002936486.1 50S ribosomal protein L10 -
  HAS68_RS05960 (HAS68_1087) rplL 1173972..1174337 (+) 366 WP_002936483.1 50S ribosomal protein L7/L12 -
  HAS68_RS05965 - 1174596..1174769 (+) 174 WP_006738653.1 hypothetical protein -
  HAS68_RS05970 (HAS68_1088) - 1174766..1175590 (+) 825 WP_009909851.1 replication initiator protein A -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31260.13 Da        Isoelectric Point: 8.6529

>NTDB_id=111610 HAS68_RS05945 WP_009909860.1 1169807..1170649(+) (dprA) [Streptococcus suis 05HAS68]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGVQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKIYPKENRELQTYIGKHHLVLTEYGPGTDPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=111610 HAS68_RS05945 WP_009909860.1 1169807..1170649(+) (dprA) [Streptococcus suis 05HAS68]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAACAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTGCGAAATGTCGCTGTAGTGTCTGAATGTAAAAATCCAGTTCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCTTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGCGTTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCCCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCCGTTATTGGAACAGGTTTGGATAAGATATATCCCAAAGAAAATAGAGAATTACAGACCTACATCGGAAAACATCATTT
GGTTCTGACTGAATATGGACCAGGTACAGACCCTCTCAAGTACCATTTCCCAGAACGCAATCGCATAATAGCTGGTTTGG
TGGAAGGATTGGTAGTCTGTGAAGCTAAGATGCGGTCTGGTAGCCTCATTACCTGTGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCCGGCTTGGACATCATTTCAGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SDJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

69.286

100

0.693
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis SK321

63.571

100

0.636
  dprA Lactococcus lactis subsp. cremoris KW2

60.357

100

0.604
  dprA Bacillus subtilis subsp. subtilis str. 168

51.741

71.786

0.371
  dprA Legionella pneumophila strain ERS1305867

41.7

88.214

0.368

Multiple sequence alignment