Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   A66_RS04335 Genome accession   NZ_LN847353
Coordinates   834002..834652 (+) Length   216 a.a.
NCBI ID   WP_000387342.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain A66     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 829002..839652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS04295 (A66_00863) - 829487..829702 (+) 216 WP_001232082.1 YozE family protein -
  A66_RS04300 (A66_00864) - 829788..830756 (+) 969 WP_000658183.1 PhoH family protein -
  A66_RS04305 (A66_00866) - 830949..831449 (+) 501 WP_000566982.1 GNAT family N-acetyltransferase -
  A66_RS11690 - 831452..831777 (+) 326 Protein_853 TfoX/Sxy family protein -
  A66_RS12485 ald 832078..833189 (-) 1112 Protein_854 alanine dehydrogenase -
  A66_RS12760 - 833366..833934 (+) 569 Protein_855 GNAT family N-acetyltransferase -
  A66_RS04335 (A66_00873) comEA/celA/cilE 834002..834652 (+) 651 WP_000387342.1 helix-hairpin-helix domain-containing protein Machinery gene
  A66_RS04340 (A66_00874) comEC/celB 834636..836876 (+) 2241 WP_053039576.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A66_RS12985 - 837055..837243 (+) 189 Protein_858 hypothetical protein -
  A66_RS04350 (A66_00875) - 837276..837863 (+) 588 WP_000945250.1 ATP-binding cassette domain-containing protein -
  A66_RS04355 (A66_00876) - 837867..839051 (+) 1185 WP_000655967.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23195.50 Da        Isoelectric Point: 6.0746

>NTDB_id=1114565 A66_RS04335 WP_000387342.1 834002..834652(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain A66]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAASQQTASGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1114565 A66_RS04335 WP_000387342.1 834002..834652(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain A66]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGAAAAGGAAGTGAAGAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGATTTGCCAGTAGGTAGTCGGGTCAATGATGCTGTTCAGAAGGCGGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTCAGTGATGAGGCTCTGGTTTACGTTCCAACTAAGGGAG
AAGAAGCAGCTAGTCAACAGACTGCTTCTGGGACGGCCTCTTCAACGAGCAAGGAAAAGAAGGTCAATCTCAACAAAGCC
AGTCTGGAAGAGCTTAAACAGGTTAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATAGACCATCGTGAGGCAAATGG
GAAATTCAAGTCGATTGATGAACTCAAGAAGGTCTCTGGCATTGGTGCTAAGACCATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

98.148

100

0.981
  comEA/celA/cilE Streptococcus mitis NCTC 12261

96.759

100

0.968
  comEA/celA/cilE Streptococcus pneumoniae Rx1

95.37

100

0.954
  comEA/celA/cilE Streptococcus pneumoniae D39

95.37

100

0.954
  comEA/celA/cilE Streptococcus pneumoniae R6

95.37

100

0.954
  comEA/celA/cilE Streptococcus mitis SK321

93.056

100

0.931
  comEA Lactococcus lactis subsp. cremoris KW2

42.222

100

0.44
  comEA Latilactobacillus sakei subsp. sakei 23K

34.764

100

0.375

Multiple sequence alignment