Detailed information NTG1114558

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: A66_RS02440
• Genome accession: NZ_LN847353
• Coordinates: 462554..464707 (-)
• Length: 717 a.a.
• NCBI ID: WP_053039478.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain A66
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 457554..469707

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A66_RS02410 (A66_00481)	-	457886..458215 (-)	330	WP_000132573.1	hypothetical protein	-
A66_RS02415 (A66_00482)	-	458492..458830 (+)	339	WP_000682133.1	LytTR family DNA-binding domain-containing protein	-
A66_RS02420 (A66_00483)	comE/blpR	458835..459572 (+)	738	WP_001219121.1	response regulator transcription factor	Regulator
A66_RS02425 (A66_00484)	-	459586..460926 (+)	1341	WP_053039477.1	sensor histidine kinase	-
A66_RS02430 (A66_00485)	blpC	460997..461125 (-)	129	WP_000358815.1	quorum-sensing system pheromone BlpC	-
A66_RS02435 (A66_00486)	-	461182..462543 (-)	1362	WP_001069075.1	bacteriocin secretion accessory protein	-
A66_RS02440 (A66_00487)	comA/nlmT	462554..464707 (-)	2154	WP_053039478.1	peptide cleavage/export ABC transporter BlpA	Regulator
A66_RS02445 (A66_00488)	-	464987..465217 (+)	231	WP_000379961.1	Blp family class II bacteriocin	-
A66_RS02450 (A66_00489)	-	465220..465339 (+)	120	WP_001829206.1	PncF family bacteriocin immunity protein	-
A66_RS02460 (A66_00490)	-	466124..466507 (+)	384	WP_000877381.1	hypothetical protein	-
A66_RS02465 (A66_00491)	-	466559..467248 (+)	690	WP_053039480.1	CPBP family intramembrane glutamic endopeptidase	-
A66_RS02470 (A66_00492)	blpZ	467291..467524 (+)	234	WP_000276498.1	immunity protein BlpZ	-
A66_RS02475 (A66_00493)	-	467675..468286 (+)	612	WP_000394039.1	CPBP family intramembrane glutamic endopeptidase	-
A66_RS02480 (A66_00494)	ccrZ	468448..469242 (+)	795	WP_000363001.1	cell cycle regulator CcrZ	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80893.87 Da
• Isoelectric Point: 7.6798

>NTDB_id=1114558 A66_RS02440 WP_053039478.1 462554..464707(-) (comA/nlmT) [Streptococcus pneumoniae strain A66]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRTVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVSIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMSYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=1114558 A66_RS02440 WP_053039478.1 462554..464707(-) (comA/nlmT) [Streptococcus pneumoniae strain A66]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGGACTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TATCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTA
TTATCTCCAAGGAATCTTAGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGAGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.608	99.721	0.714
comA	Streptococcus mitis NCTC 12261	66.48	99.442	0.661
comA	Streptococcus pneumoniae Rx1	65.919	99.442	0.656
comA	Streptococcus pneumoniae R6	65.919	99.442	0.656
comA	Streptococcus pneumoniae D39	65.919	99.442	0.656
comA	Streptococcus mitis SK321	65.919	99.442	0.656
comA	Streptococcus gordonii str. Challis substr. CH1	65.181	100	0.653
comA	Streptococcus pneumoniae TIGR4	65.638	99.442	0.653