Detailed information
Bioinformatically predicted
Overview
| Name | comW | Type | Regulator |
| Locus tag | A66_RS00125 | Genome accession | NZ_LN847353 |
| Coordinates | 21656..21892 (+) | Length | 78 a.a. |
| NCBI ID | WP_000939545.1 | Uniprot ID | - |
| Organism | Streptococcus pneumoniae strain A66 | ||
| Function | stabilization and activation of ComX (predicted from homology) Competence regulation |
||
Genomic Context
Location: 16656..26892
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A66_RS00095 (A66_00018) | hpt | 17100..17642 (+) | 543 | WP_000892185.1 | hypoxanthine phosphoribosyltransferase | - |
| A66_RS00100 (A66_00019) | ftsH | 17658..19616 (+) | 1959 | WP_000744557.1 | ATP-dependent zinc metalloprotease FtsH | - |
| A66_RS00105 (A66_00020) | comX/comX2 | 19738..20217 (+) | 480 | WP_000588897.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| A66_RS10485 (A66_00021) | - | 20307..20558 (+) | 252 | Protein_20 | transposase | - |
| A66_RS10490 | - | 20593..21390 (-) | 798 | Protein_21 | transposase | - |
| A66_RS00125 (A66_00025) | comW | 21656..21892 (+) | 237 | WP_000939545.1 | sigma(X)-activator ComW | Regulator |
| A66_RS00130 (A66_00026) | - | 22123..23409 (+) | 1287 | WP_014931787.1 | adenylosuccinate synthase | - |
| A66_RS00135 (A66_00027) | tadA | 23610..24077 (+) | 468 | WP_000291875.1 | tRNA adenosine(34) deaminase TadA | - |
| A66_RS00140 (A66_00028) | - | 24264..24707 (+) | 444 | WP_000701992.1 | dUTP diphosphatase | - |
| A66_RS00145 (A66_00029) | - | 24709..25224 (+) | 516 | WP_000691236.1 | histidine phosphatase family protein | - |
| A66_RS00150 (A66_00030) | radA | 25238..26599 (+) | 1362 | WP_074192812.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 78 a.a. Molecular weight: 9658.13 Da Isoelectric Point: 6.7051
>NTDB_id=1114548 A66_RS00125 WP_000939545.1 21656..21892(+) (comW) [Streptococcus pneumoniae strain A66]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC
Nucleotide
Download Length: 237 bp
>NTDB_id=1114548 A66_RS00125 WP_000939545.1 21656..21892(+) (comW) [Streptococcus pneumoniae strain A66]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comW | Streptococcus pneumoniae Rx1 |
100 |
100 |
1 |
| comW | Streptococcus pneumoniae D39 |
100 |
100 |
1 |
| comW | Streptococcus pneumoniae R6 |
100 |
100 |
1 |
| comW | Streptococcus pneumoniae TIGR4 |
100 |
100 |
1 |
| comW | Streptococcus mitis SK321 |
75.641 |
100 |
0.756 |
| comW | Streptococcus mitis NCTC 12261 |
75.325 |
98.718 |
0.744 |