Detailed information NTG1114347

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: AT689_RS02160
• Genome accession: NZ_LN831051
• Coordinates: 418894..421047 (-)
• Length: 717 a.a.
• NCBI ID: WP_000668306.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NCTC7465
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 413894..426047

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AT689_RS13640	-	416534..416644 (-)	111	WP_078065395.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
AT689_RS02150 (ERS445053_00424)	purC	416655..417362 (-)	708	WP_000043300.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
AT689_RS02155 (ERS445053_00425)	comB	417532..418881 (-)	1350	WP_000801605.1	competence pheromone export protein ComB	Regulator
AT689_RS02160 (ERS445053_00426)	comA	418894..421047 (-)	2154	WP_000668306.1	peptide cleavage/export ABC transporter ComA	Regulator
AT689_RS13295	-	421632..421757 (-)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
AT689_RS02170 (ERS445053_00427)	blpU	421760..421990 (-)	231	WP_001093075.1	bacteriocin-like peptide BlpU	-
AT689_RS02175 (ERS445053_00428)	-	422193..422492 (-)	300	Protein_437	transposase family protein	-
AT689_RS02180 (ERS445053_00429)	-	422529..422762 (-)	234	WP_000136447.1	acyl carrier protein	-
AT689_RS02185 (ERS445053_00430)	plsX	422768..423760 (-)	993	WP_000717461.1	phosphate acyltransferase PlsX	-
AT689_RS02190 (ERS445053_00431)	recO	423757..424527 (-)	771	WP_000616164.1	DNA repair protein RecO	-
AT689_RS02195 (ERS445053_00432)	-	424524..425693 (-)	1170	WP_000366351.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80386.40 Da
• Isoelectric Point: 6.2140

>NTDB_id=1114347 AT689_RS02160 WP_000668306.1 418894..421047(-) (comA) [Streptococcus pneumoniae strain NCTC7465]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKTTMDGTTALGLVKVAEEMGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFENMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGEMTFKQVHYKYGYGRDVLSDINLTVPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAELREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=1114347 AT689_RS02160 WP_000668306.1 418894..421047(-) (comA) [Streptococcus pneumoniae strain NCTC7465]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAAGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGTTATTATTTTTTGGCTCACTTGCGAGAATTGGCTAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATGGGTTTTGAGACGCGAGCCATTAAGGCGGATATGACGCTTTTTGACTTGCCGGATTTG
ACTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGATAG
CATTCATATTGCCGACCCAGATCCTGGGGTGAAATTGACCAAACTGCCACGTGAGCGTTTTGAGGAAGAATGGACAGGAG
TGACTCTTTTTATGGCACCTAGTCCAGACTATAAGCCTCATAAGGAACAAAAAAATGGTCTGCTCTCTTTCATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAATATCGTTTTGGCAACACTCTTGGTAACCGTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGTTGGGGATTATTTCTATTGGGCTGGTCA
TCGTCTACATCCTCCAGCAAATCTTGTCTTACGCTCAGGAGTATCTCTTGCTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTGATTTTGTCCTATATCAAGCATGTTTTTCACCTCCCTATGTCCTTCTTTGCGACACGCAGGACAGGGGAGATCGTGTC
TCGTTTTACAGATGCTAACAGTATCATCGATGCGCTGGCTTCGACAATCCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCCCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCGCTTCCTATCTACACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAATATGAATCGGGACACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAACGGTATTGAGACTATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAAATTGACAAGGAAT
TTGTGGATTATCTGAAGAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAGGTTGCCCATCTC
TTGCTTAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAAGTGTATCTAGTAGCTTCTGAGTTTGAGGAGAAGAAAACGGTTGAGGATTTGAGCTTGATG
AAGGGAGAGATGACTTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGACGTCTTGTCGGATATCAATTTAACCGT
TCCCCAAGGGTCTAAGGTGGCTTTTGTGGGGATTTCAGGGTCAGGTAAGACGACTTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAAGGGGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTGCGCCAGTACATC
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCCAAGGAGGGGACGAC
ACAGGAAGATATCTTACGGGCGGTCGAATTGGCAGAGCTTCGAGAGGATATCGAGCGCATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGGGCAGGAATTTCAGGTGGTCAACGTCAGAGAATCGCTTTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTCGATAATCTCATGGCTTT
GGACAAGACCTTGATTTTCATTGCTCACCGCTTGACTATTGCTGAGCGGACAGAGAAGGTGGTTGTCTTGGATCAGGGCA
AGATTGTCGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGGAGGCTTTTACGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae Rx1	99.303	100	0.993
comA	Streptococcus pneumoniae D39	99.303	100	0.993
comA	Streptococcus pneumoniae R6	99.303	100	0.993
comA	Streptococcus pneumoniae TIGR4	98.884	100	0.989
comA	Streptococcus mitis SK321	98.326	100	0.983
comA	Streptococcus mitis NCTC 12261	98.047	100	0.98
comA	Streptococcus gordonii str. Challis substr. CH1	80.335	100	0.803
comA/nlmT	Streptococcus mutans UA159	64.435	100	0.644