Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   AT689_RS02155 Genome accession   NZ_LN831051
Coordinates   417532..418881 (-) Length   449 a.a.
NCBI ID   WP_000801605.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 412532..423881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS02145 (ERS445053_00423) - 412728..416453 (-) 3726 WP_000361197.1 phosphoribosylformylglycinamidine synthase -
  AT689_RS13640 - 416534..416644 (-) 111 WP_078065395.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  AT689_RS02150 (ERS445053_00424) purC 416655..417362 (-) 708 WP_000043300.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  AT689_RS02155 (ERS445053_00425) comB 417532..418881 (-) 1350 WP_000801605.1 competence pheromone export protein ComB Regulator
  AT689_RS02160 (ERS445053_00426) comA 418894..421047 (-) 2154 WP_000668306.1 peptide cleavage/export ABC transporter ComA Regulator
  AT689_RS13295 - 421632..421757 (-) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  AT689_RS02170 (ERS445053_00427) blpU 421760..421990 (-) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  AT689_RS02175 (ERS445053_00428) - 422193..422492 (-) 300 Protein_437 transposase family protein -
  AT689_RS02180 (ERS445053_00429) - 422529..422762 (-) 234 WP_000136447.1 acyl carrier protein -
  AT689_RS02185 (ERS445053_00430) plsX 422768..423760 (-) 993 WP_000717461.1 phosphate acyltransferase PlsX -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49557.39 Da        Isoelectric Point: 5.5485

>NTDB_id=1114346 AT689_RS02155 WP_000801605.1 417532..418881(-) (comB) [Streptococcus pneumoniae strain NCTC7465]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGHQATFRDYISQAGSIRASTSQQN
ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1114346 AT689_RS02155 WP_000801605.1 417532..418881(-) (comB) [Streptococcus pneumoniae strain NCTC7465]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCCAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCCACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTATTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAATCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATTGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTATGGGGTGGAAGGCCG
TTTACAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.886

100

0.989
  comB Streptococcus pneumoniae Rx1

98.664

100

0.987
  comB Streptococcus pneumoniae D39

98.664

100

0.987
  comB Streptococcus pneumoniae R6

98.664

100

0.987
  comB Streptococcus mitis SK321

94.432

100

0.944
  comB Streptococcus mitis NCTC 12261

93.987

100

0.94
  comB Streptococcus gordonii str. Challis substr. CH1

55.111

100

0.552

Multiple sequence alignment