Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   HMPREF9318_RS10750 Genome accession   NZ_KB373319
Coordinates   563277..563987 (+) Length   236 a.a.
NCBI ID   WP_006740362.1    Uniprot ID   -
Organism   Streptococcus urinalis FB127-CNA-2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 558277..568987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9318_RS10725 (HMPREF9318_02146) - 558960..559940 (+) 981 WP_006740273.1 DUF3114 domain-containing protein -
  HMPREF9318_RS10730 (HMPREF9318_02147) - 559970..560620 (-) 651 WP_006738599.1 amino acid ABC transporter permease -
  HMPREF9318_RS10735 (HMPREF9318_02148) - 560633..561328 (-) 696 WP_006739051.1 amino acid ABC transporter permease -
  HMPREF9318_RS10740 (HMPREF9318_02149) - 561426..562175 (-) 750 WP_006740471.1 transporter substrate-binding domain-containing protein -
  HMPREF9318_RS10745 (HMPREF9318_02150) - 562185..562970 (-) 786 WP_006740230.1 amino acid ABC transporter ATP-binding protein -
  HMPREF9318_RS10750 (HMPREF9318_02151) vicR 563277..563987 (+) 711 WP_006740362.1 response regulator YycF Regulator
  HMPREF9318_RS10755 (HMPREF9318_02152) vicK 563980..565329 (+) 1350 WP_006738842.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HMPREF9318_RS10760 (HMPREF9318_02153) vicX 565333..566142 (+) 810 WP_006739451.1 MBL fold metallo-hydrolase Regulator
  HMPREF9318_RS10765 (HMPREF9318_02154) rnc 566261..566947 (+) 687 WP_006738912.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27054.81 Da        Isoelectric Point: 5.2608

>NTDB_id=1113402 HMPREF9318_RS10750 WP_006740362.1 563277..563987(+) (vicR) [Streptococcus urinalis FB127-CNA-2]
MKKILIVDDEKPISDIIKFNLAKEGYDTVTAFDGREAIAKFEEENPDLIILDLMLPELDGLEVAKEVRKSSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHIRRNDSITSSSNNDGKASTNSELNIGELQILPEAFVAKKRQKEIE
LTHREFELLHHLANHLGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSNE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1113402 HMPREF9318_RS10750 WP_006740362.1 563277..563987(+) (vicR) [Streptococcus urinalis FB127-CNA-2]
ATGAAAAAAATTCTGATTGTTGATGATGAAAAGCCAATCTCAGATATCATTAAGTTTAATTTAGCTAAAGAAGGGTATGA
TACTGTCACGGCATTTGATGGTCGCGAAGCTATTGCTAAATTTGAAGAAGAAAATCCAGATTTGATTATTTTGGATTTGA
TGTTACCAGAATTAGATGGACTAGAAGTAGCAAAAGAAGTTCGTAAGAGCAGTCATATTCCTATTATTATGCTTTCTGCA
AAGGATAGTGAATTTGATAAGGTGATTGGACTTGAAATTGGTGCAGATGATTATGTGACTAAACCCTTTTCAAATAGAGA
ATTGTTAGCGCGTGTTAAAGCACATATTAGACGTAATGATTCGATTACTTCTTCATCAAATAATGATGGAAAAGCATCAA
CTAACTCTGAACTTAATATTGGAGAACTACAAATTTTACCCGAGGCTTTTGTCGCCAAAAAACGTCAAAAAGAAATTGAA
TTAACTCACCGTGAATTTGAGTTACTTCATCATTTGGCAAACCATCTAGGTCAAGTTATGACGAGAGAACATTTATTAGA
GACTGTTTGGGGTTATGATTATTTTGGTGATGTCAGAACGGTTGATGTTACCGTTCGTCGTCTCCGTGAGAAAATTGAAG
ACACACCAAGCCGTCCTGAATACATTTTGACAAGACGTGGTGTTGGGTATTACATGAAATCAAATGAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(157-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

87.179

99.153

0.864
  micA Streptococcus pneumoniae Cp1015

75.527

100

0.758
  covR Streptococcus salivarius strain HSISS4

46.121

98.305

0.453
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.064

98.729

0.445

Multiple sequence alignment