Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   FOA32_RS07240 Genome accession   NZ_JABTYC020000010
Coordinates   17680..19035 (+) Length   451 a.a.
NCBI ID   WP_217473236.1    Uniprot ID   -
Organism   Streptococcus sinensis strain Forsyth1A     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 12680..24035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOA32_RS07225 (FOA32_001442) - 13780..14310 (+) 531 WP_037614996.1 TetR/AcrR family transcriptional regulator -
  FOA32_RS07230 (FOA32_001443) rpsD 14482..15093 (-) 612 WP_037614998.1 30S ribosomal protein S4 -
  FOA32_RS07235 (FOA32_001444) comA 15513..17666 (+) 2154 WP_217473235.1 peptide cleavage/export ABC transporter ComA Regulator
  FOA32_RS07240 (FOA32_001445) comB 17680..19035 (+) 1356 WP_217473236.1 bacteriocin secretion accessory protein Regulator
  FOA32_RS07245 (FOA32_001446) - 19084..19812 (-) 729 WP_217473237.1 ABC transporter ATP-binding protein -
  FOA32_RS07250 (FOA32_001447) - 19812..20810 (-) 999 WP_217473238.1 ABC transporter substrate-binding protein -
  FOA32_RS07255 (FOA32_001448) - 20854..21606 (-) 753 WP_217473239.1 ABC transporter permease -
  FOA32_RS07260 (FOA32_001449) - 21569..21859 (-) 291 WP_062201597.1 thiamine-binding protein -
  FOA32_RS07265 (FOA32_001450) - 22117..22740 (-) 624 WP_217473240.1 HAD family hydrolase -
  FOA32_RS07270 (FOA32_001451) - 23010..23288 (-) 279 WP_217473241.1 Veg family protein -

Sequence

Protein


Download         Length: 451 a.a.        Molecular weight: 50545.69 Da        Isoelectric Point: 6.0841

>NTDB_id=1112706 FOA32_RS07240 WP_217473236.1 17680..19035(+) (comB) [Streptococcus sinensis strain Forsyth1A]
MPQDFLESAEFYNRRYHNFSSRVIIPITLLFLFTLLFGLFAQKEITVSSSASLEPSRIISNIQSTSNNTIIMNHLAENKC
VKQGDLLIQYQNGAEELQKDSYSNQLDMLQDQKKQLEYLQASLQTGNDQFPEADNFGYRQSFRDYQSQAVSLRSNTDQQN
AAIASQNAAASSAQTENAKLISETQAKISDYRSVKIAIQNDSVVDGSNAGYSLYQTYQAQVNMDTQDQLKSQILAQADTQ
IAQLEGTLASYRIQYAGSGARQAYSTGLNSQLESLKAQQLTKVAQELTDLEQKILETETGKKVQDGMIQKTVITAPENGI
LHLNPETSHSTLVPEGSLLAQLYPVLTTEKKIKITAYISSKDIAHLKVGNPIRFTTINDINKQETLTSKISNIDTTASKT
EKGNFFKLEAETTLTDKEAKQLRYGLEGRIVMITGKKTYFQYYRDQFLKKD

Nucleotide


Download         Length: 1356 bp        

>NTDB_id=1112706 FOA32_RS07240 WP_217473236.1 17680..19035(+) (comB) [Streptococcus sinensis strain Forsyth1A]
GTGCCCCAAGATTTTTTAGAAAGCGCTGAGTTTTACAACCGTCGCTATCACAATTTCTCTAGTAGGGTTATTATTCCTAT
TACTTTGCTCTTTCTTTTCACCCTACTCTTCGGACTCTTTGCTCAAAAAGAGATTACTGTCTCATCAAGTGCCAGTCTAG
AGCCTAGTCGTATCATTTCTAACATCCAGTCCACGAGTAATAATACGATCATTATGAATCATCTCGCAGAAAACAAGTGT
GTCAAACAAGGTGACCTGCTTATTCAATATCAAAATGGAGCAGAAGAGCTACAGAAGGATAGCTACTCTAACCAGCTAGA
TATGCTCCAAGATCAGAAAAAACAATTGGAGTATTTACAAGCTAGTCTCCAAACTGGGAATGATCAGTTCCCAGAAGCTG
ATAATTTTGGCTACCGGCAATCTTTTCGGGATTATCAAAGTCAGGCAGTCAGTCTCCGTAGTAATACAGACCAGCAAAAC
GCAGCCATTGCTTCACAAAACGCCGCTGCTAGCAGTGCACAGACAGAGAATGCAAAGCTCATTTCTGAGACCCAAGCTAA
AATTTCAGACTATAGATCAGTCAAGATAGCTATTCAAAATGACTCAGTAGTAGATGGTAGCAACGCAGGCTATTCCCTAT
ACCAAACCTATCAAGCACAAGTAAACATGGACACGCAAGACCAGCTAAAAAGTCAAATACTGGCACAAGCAGATACACAG
ATTGCTCAATTAGAAGGAACACTGGCAAGCTACCGCATCCAATATGCAGGTTCAGGTGCTCGGCAAGCCTACTCGACTGG
GTTAAACAGTCAGCTAGAATCACTCAAAGCTCAGCAACTAACTAAGGTTGCTCAAGAATTAACTGATTTAGAGCAAAAAA
TTCTTGAAACAGAAACTGGGAAAAAGGTGCAAGATGGGATGATTCAAAAAACTGTCATTACAGCACCTGAAAATGGGATA
CTTCACCTCAATCCTGAGACTAGCCATTCCACCTTAGTACCTGAGGGAAGTCTCCTTGCCCAACTCTATCCTGTCCTGAC
CACGGAAAAGAAAATTAAGATTACCGCTTATATTTCTTCCAAGGATATCGCTCATCTTAAAGTCGGTAACCCTATTCGCT
TCACAACCATAAACGATATTAACAAGCAAGAAACTCTGACTTCCAAGATTAGCAACATCGATACTACTGCAAGCAAGACA
GAAAAAGGAAATTTTTTCAAATTAGAAGCAGAGACTACATTGACAGACAAAGAAGCTAAGCAACTCCGCTATGGTTTAGA
AGGAAGAATTGTAATGATCACAGGTAAGAAAACTTACTTCCAATACTATAGAGATCAATTTTTGAAAAAAGACTAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-425)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

61.641

100

0.616
  comB Streptococcus pneumoniae D39

61.641

100

0.616
  comB Streptococcus pneumoniae R6

61.641

100

0.616
  comB Streptococcus pneumoniae TIGR4

61.419

100

0.614
  comB Streptococcus mitis SK321

60.754

100

0.608
  comB Streptococcus mitis NCTC 12261

60.532

100

0.605
  comB Streptococcus gordonii str. Challis substr. CH1

53.898

99.557

0.537

Multiple sequence alignment