Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   FOA32_RS07235 Genome accession   NZ_JABTYC020000010
Coordinates   15513..17666 (+) Length   717 a.a.
NCBI ID   WP_217473235.1    Uniprot ID   -
Organism   Streptococcus sinensis strain Forsyth1A     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 10513..22666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOA32_RS07220 (FOA32_001441) - 11237..13636 (-) 2400 WP_217473234.1 YhgE/Pip domain-containing protein -
  FOA32_RS07225 (FOA32_001442) - 13780..14310 (+) 531 WP_037614996.1 TetR/AcrR family transcriptional regulator -
  FOA32_RS07230 (FOA32_001443) rpsD 14482..15093 (-) 612 WP_037614998.1 30S ribosomal protein S4 -
  FOA32_RS07235 (FOA32_001444) comA 15513..17666 (+) 2154 WP_217473235.1 peptide cleavage/export ABC transporter ComA Regulator
  FOA32_RS07240 (FOA32_001445) comB 17680..19035 (+) 1356 WP_217473236.1 bacteriocin secretion accessory protein Regulator
  FOA32_RS07245 (FOA32_001446) - 19084..19812 (-) 729 WP_217473237.1 ABC transporter ATP-binding protein -
  FOA32_RS07250 (FOA32_001447) - 19812..20810 (-) 999 WP_217473238.1 ABC transporter substrate-binding protein -
  FOA32_RS07255 (FOA32_001448) - 20854..21606 (-) 753 WP_217473239.1 ABC transporter permease -
  FOA32_RS07260 (FOA32_001449) - 21569..21859 (-) 291 WP_062201597.1 thiamine-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80999.17 Da        Isoelectric Point: 7.6986

>NTDB_id=1112705 FOA32_RS07235 WP_217473235.1 15513..17666(+) (comA) [Streptococcus sinensis strain Forsyth1A]
MKFRRRHYRPQVDQMDCGVTSLAMVFGYYGSYYSLAHLRELAKTTMEGTTAFGLVRVAEKLNFETRTIRADMSLFEHNDL
TYPFVAHVVKNGKLLHYYVVTGQDKKFIHIADPDPTVKMTKLPREHFESEWTGVAIFIAPTPDYKPYKEQKQGLLSFLPI
LIRQKSLMTNIVLATFLVTIINIIGSYYLQSIIDTYVPDQMRSTLGIISLGLVLVYILQQVLSYAQDYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIVLIISVVLFSQNTNLFFISLLALPIYTL
LIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGMETIKSLTSEKLRYQKIDKEFVDYLKKSFVYSRAESQQKALKKVAQL
LLNVAILWMGAGLVMNKQMTLGQLITYNTLLIYFTNPLENIINLQTKLQTAQVANNRLNEVYLVESEFEEKKIISDLSLM
TGDIEFKNVSYKYGYRRDVLANINLTIKQKSKVAFVGISGSGKTTLAKMIVNFYDPSAGQISLGGVNLNQIDKHALRQHI
NYLPQQPYVFNGTIMDNLLLGAKEGTTQEDVLRAVELAEIRADIENMPLSYQTELTSDGAGISGGQRQRIALARALLTDA
PILILDEATSSLDILTEKRIVDNLLALDKTLIFIAHRLTIAERTEHVVVMDHGRIVEQGSHTDLLDQGGFYANLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1112705 FOA32_RS07235 WP_217473235.1 15513..17666(+) (comA) [Streptococcus sinensis strain Forsyth1A]
ATGAAATTTCGCCGTCGACACTACCGTCCTCAGGTGGACCAAATGGATTGCGGCGTGACATCTTTGGCCATGGTTTTTGG
TTACTACGGCTCCTATTACTCACTAGCGCATCTACGAGAGTTAGCCAAAACTACCATGGAGGGCACGACAGCTTTTGGTT
TGGTTAGGGTCGCTGAGAAGCTAAACTTTGAGACGCGAACCATAAGAGCAGATATGTCCCTCTTTGAGCACAATGACTTA
ACTTACCCTTTCGTAGCGCATGTAGTCAAAAATGGCAAATTGCTACACTACTATGTAGTGACTGGGCAAGATAAGAAATT
TATCCATATTGCTGACCCTGACCCTACGGTCAAGATGACCAAGCTACCTAGGGAACATTTTGAGTCAGAATGGACAGGAG
TGGCAATATTCATAGCACCGACGCCTGACTACAAACCGTATAAAGAGCAAAAGCAAGGACTTCTTTCTTTCCTTCCTATT
TTGATTAGACAAAAGAGCTTGATGACCAATATCGTTCTTGCAACCTTTCTGGTGACCATCATCAACATCATCGGCTCCTA
CTATCTCCAGTCTATTATTGACACCTATGTACCTGACCAGATGCGGAGTACGCTAGGGATCATCTCGCTGGGCTTGGTCT
TGGTGTATATTTTACAGCAAGTTTTGAGTTACGCTCAGGATTATCTGCTTTTGATTTTGGGACAACGTTTGTCTATTGAT
GTCATTTTGTCCTATATCAAGCATGTTTTTCACCTTCCAATGTCTTTCTTTGCAACACGGCGGACAGGAGAAATCGTTTC
TCGTTTTACTGATGCTAATAGTATCATTGATGCTCTTGCAAGTACCATCTTATCTATATTTCTCGATGTTTCAATCGTAC
TAATCATCTCAGTAGTCCTGTTCTCACAAAACACCAACCTCTTTTTTATTAGTCTCTTGGCTCTGCCTATCTACACACTC
CTTATCTTTGCCTTTATGAAACCCTTTGAAAAGATGAACCGTGACACTATGGAGGCCAATGCTGTGCTATCCTCTTCCAT
TATTGAGGATATTAACGGCATGGAGACTATTAAGTCTCTTACCAGTGAAAAACTTCGCTATCAGAAGATTGATAAAGAAT
TCGTAGATTATTTAAAAAAGTCCTTTGTCTATAGTAGAGCAGAAAGTCAGCAAAAAGCTCTGAAAAAAGTAGCTCAGTTA
CTTCTGAATGTTGCTATCCTCTGGATGGGGGCGGGGCTGGTCATGAATAAGCAGATGACTCTGGGACAGCTCATCACCTA
CAACACCCTCTTGATCTATTTCACAAATCCGCTGGAAAACATCATCAATCTCCAAACCAAACTCCAAACAGCTCAGGTAG
CTAATAATCGACTCAACGAGGTCTATTTAGTAGAATCTGAGTTTGAGGAGAAAAAGATCATATCTGATCTTAGTTTGATG
ACAGGCGACATTGAGTTTAAAAATGTTAGCTACAAATATGGGTATAGACGAGATGTTCTAGCCAATATCAACCTAACCAT
CAAGCAGAAATCAAAGGTTGCTTTTGTTGGGATTTCCGGCTCAGGTAAAACTACGCTTGCTAAAATGATTGTCAATTTTT
ACGACCCTAGTGCTGGGCAGATTAGTCTAGGTGGGGTTAATCTCAACCAGATTGACAAACATGCTCTCCGCCAGCATATC
AACTATCTTCCACAACAGCCCTATGTCTTTAACGGCACGATCATGGACAACCTGCTTTTGGGCGCCAAAGAAGGTACTAC
GCAAGAAGATGTTTTGCGTGCTGTCGAACTAGCAGAGATTCGTGCAGACATTGAAAACATGCCTCTAAGTTACCAGACTG
AGCTAACCTCTGATGGAGCTGGGATTTCGGGCGGTCAACGTCAACGAATCGCCTTAGCAAGGGCTCTATTGACGGATGCT
CCTATTTTGATTTTAGATGAGGCTACTAGCAGCTTGGATATTTTAACAGAAAAACGAATTGTTGATAATCTGCTAGCTTT
GGATAAAACCTTAATTTTTATCGCCCATCGTCTGACAATTGCCGAGCGAACCGAGCATGTCGTAGTGATGGATCACGGCC
GCATTGTAGAGCAGGGCAGCCATACAGATCTGCTGGATCAGGGCGGCTTCTATGCCAATCTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(169-438)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

86.192

100

0.862
  comA Streptococcus pneumoniae Rx1

85.774

100

0.858
  comA Streptococcus pneumoniae D39

85.774

100

0.858
  comA Streptococcus pneumoniae R6

85.774

100

0.858
  comA Streptococcus mitis SK321

85.635

100

0.856
  comA Streptococcus pneumoniae TIGR4

85.356

100

0.854
  comA Streptococcus gordonii str. Challis substr. CH1

76.709

100

0.767
  comA/nlmT Streptococcus mutans UA159

64.575

100

0.646

Multiple sequence alignment