Detailed information NTG1111869

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SPYH293_RS04325
• Genome accession: NZ_HG316453
• Coordinates: 867500..868336 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain H293
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 862500..873336

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYH293_RS04295 (SPYH293_00884)	-	862985..863422 (+)	438	WP_031488279.1	hypothetical protein	-
SPYH293_RS04300 (SPYH293_00885)	-	863472..864383 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
SPYH293_RS04305 (SPYH293_00886)	trhA	864500..865150 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
SPYH293_RS04310 (SPYH293_00887)	-	865147..865587 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
SPYH293_RS04315 (SPYH293_00888)	ylqF	865806..866654 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
SPYH293_RS04320 (SPYH293_00889)	-	866644..867435 (+)	792	WP_031488275.1	ribonuclease HII	-
SPYH293_RS04325 (SPYH293_00890)	dprA	867500..868336 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
SPYH293_RS04330 (SPYH293_00891)	topA	868443..870572 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
SPYH293_RS08835	-	870647..871504 (-)	858	Protein_817	LysR family transcriptional regulator	-
SPYH293_RS04340 (SPYH293_00893)	-	871544..872089 (+)	546	Protein_818	PTS sugar transporter subunit IIC	-
SPYH293_RS04345 (SPYH293_00894)	-	872104..873096 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=1111869 SPYH293_RS04325 WP_031488274.1 867500..868336(+) (dprA) [Streptococcus pyogenes strain H293]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1111869 SPYH293_RS04325 WP_031488274.1 867500..868336(+) (dprA) [Streptococcus pyogenes strain H293]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363