Detailed information NTG1111772

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: HMPREF9425_RS08205
• Genome accession: NZ_GL831112
• Coordinates: 1703226..1703975 (-)
• Length: 249 a.a.
• NCBI ID: WP_003098133.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis ATCC 49124
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1698226..1708975

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS08185 (HMPREF9425_1715)	-	1698547..1699779 (-)	1233	WP_003098127.1	cysteine desulfurase	-
HMPREF9425_RS08190 (HMPREF9425_1716)	sufD	1699833..1701095 (-)	1263	WP_003098130.1	Fe-S cluster assembly protein SufD	-
HMPREF9425_RS08195 (HMPREF9425_1717)	sufC	1701132..1701902 (-)	771	WP_002883600.1	Fe-S cluster assembly ATPase SufC	-
HMPREF9425_RS08200 (HMPREF9425_1718)	-	1702065..1703222 (-)	1158	WP_003098132.1	glycosyltransferase family 4 protein	-
HMPREF9425_RS08205 (HMPREF9425_1719)	mecA	1703226..1703975 (-)	750	WP_003098133.1	adaptor protein MecA	Regulator
HMPREF9425_RS09575	-	1704256..1704579 (+)	324	WP_081448742.1	DUF3021 family protein	-
HMPREF9425_RS10745 (HMPREF9425_1720)	-	1704529..1705204 (-)	676	Protein_1676	transposase	-
HMPREF9425_RS08215 (HMPREF9425_1721)	-	1705200..1705662 (+)	463	Protein_1677	DUF1697 domain-containing protein	-
HMPREF9425_RS08220 (HMPREF9425_1722)	-	1705704..1706444 (-)	741	WP_003098139.1	MerR family transcriptional regulator	-
HMPREF9425_RS10090	-	1706548..1706851 (+)	304	Protein_1679	sodium-dependent transporter	-
HMPREF9425_RS08230 (HMPREF9425_1724)	-	1707029..1707595 (+)	567	WP_003098143.1	TetR/AcrR family transcriptional regulator	-
HMPREF9425_RS08235 (HMPREF9425_1725)	-	1707780..1708130 (+)	351	WP_003098145.1	hypothetical protein	-
HMPREF9425_RS08240 (HMPREF9425_1726)	-	1708140..1708486 (+)	347	Protein_1682	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
HMPREF9425_RS10540 (HMPREF9425_1727)	-	1708681..1708812 (+)	132	WP_003098148.1	hypothetical protein	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29043.63 Da
• Isoelectric Point: 4.0182

>NTDB_id=1111772 HMPREF9425_RS08205 WP_003098133.1 1703226..1703975(-) (mecA) [Streptococcus vestibularis ATCC 49124]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLGFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEEIEKALEEVDKTMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDIYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
SVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=1111772 HMPREF9425_RS08205 WP_003098133.1 1703226..1703975(-) (mecA) [Streptococcus vestibularis ATCC 49124]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGGGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGACCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGATGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAGGGTAACTTTATGGACAAGGGAGATATTGAAGCTCACCATAAGCTCGAAGAGATTGAAAAGGCCTTGGAAGAGGTTG
ATAAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTAACCTTTACGCAAGGTTTGAAGGATGTGCCAGTGGAAGGTTCTGAACTTTATAAACTTGG
TGATATCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGACTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
TCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-243)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMD-9	94.378	100	0.944
mecA	Streptococcus thermophilus LMG 18311	93.574	100	0.936
mecA	Streptococcus mutans UA159	59.426	97.992	0.582
mecA	Streptococcus pneumoniae Rx1	45.783	100	0.458
mecA	Streptococcus pneumoniae D39	45.783	100	0.458
mecA	Streptococcus pneumoniae R6	45.783	100	0.458
mecA	Streptococcus pneumoniae TIGR4	45.783	100	0.458