Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   HMPREF9425_RS02860 Genome accession   NZ_GL831112
Coordinates   540951..542819 (+) Length   622 a.a.
NCBI ID   WP_003093571.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 535951..547819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS02845 (HMPREF9425_0592) fmt 537923..538858 (+) 936 WP_003096612.1 methionyl-tRNA formyltransferase -
  HMPREF9425_RS02850 (HMPREF9425_0593) rsmB 538848..540170 (+) 1323 WP_037621653.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  HMPREF9425_RS02855 (HMPREF9425_0594) - 540214..540951 (+) 738 WP_003094327.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HMPREF9425_RS02860 (HMPREF9425_0595) stkP/pknB 540951..542819 (+) 1869 WP_003093571.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HMPREF9425_RS02865 (HMPREF9425_0596) - 543157..543723 (+) 567 WP_003096616.1 potassium channel family protein -
  HMPREF9425_RS02870 (HMPREF9425_0597) liaF 543877..544575 (+) 699 WP_003096617.1 cell wall-active antibiotics response protein LiaF -
  HMPREF9425_RS02875 (HMPREF9425_0598) - 544572..545582 (+) 1011 WP_003093548.1 sensor histidine kinase -
  HMPREF9425_RS02880 (HMPREF9425_0599) - 545572..546216 (+) 645 WP_003096619.1 response regulator transcription factor -
  HMPREF9425_RS02895 (HMPREF9425_0600) rimM 546892..547410 (+) 519 WP_003096621.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 622 a.a.        Molecular weight: 67859.57 Da        Isoelectric Point: 6.4574

>NTDB_id=1111740 HMPREF9425_RS02860 WP_003093571.1 540951..542819(+) (stkP/pknB) [Streptococcus vestibularis ATCC 49124]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKRFIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHSRDSKVVFDDMMDTKTLPKVDSVPSVGPEKKVSPKPSEPTPAP
SKQPREKASLAKKKKNPFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVNEVEND
SVDKGKVIKTDPTAGTTRKEGTSIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDDAKEGEILS
QSPEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNRKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
DPQVGTAVDGTVILYVSVVTESSSIQQSSSASTTHSSSSTSSSSESTASSTETATEATHTEQ

Nucleotide


Download         Length: 1869 bp        

>NTDB_id=1111740 HMPREF9425_RS02860 WP_003093571.1 540951..542819(+) (stkP/pknB) [Streptococcus vestibularis ATCC 49124]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGACGTGGCGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCTGAGCTTAGCCATCCGAATATCGTTGCGATTCGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAGATTCATTCAAGACCATGCTCC
GTTGTCTAACCAAGATGTTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGCATTATTC
ACCGTGACCTTAAGCCACAGAATGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGTCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTCGAAATGTTGACAGGGCATATTCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAATGTTCCT
CAAGCGTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAATAGCACTTTGGAAATGAGTCG
CGACCTAGTAACTAGTTTACATCCTAGTCATAGTCGTGATTCTAAAGTAGTTTTTGATGACATGATGGATACTAAGACCC
TGCCAAAGGTTGATTCAGTTCCATCAGTAGGTCCTGAGAAAAAGGTTTCTCCTAAACCATCAGAGCCAACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTAGCTAAAAAGAAGAAAAATCCCTTTTCAACTCTACTCAAGGTTTTCCTAGG
CTTAGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTTCAGGTGCCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAAGTTGGCGATGTTAATGAAGTCGAGAATGAT
TCAGTCGATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAACGCGTAAAGAGGGAACAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACTT
CGAATTATGGGGTTTCCGAGGATCAAATTGATATTCAACATGTTGAAGACGATGATGCTAAAGAAGGTGAAATCCTATCT
CAAAGTCCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTCCGTGTGGCAACTCCTAAGAC
CATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATCGTAAAGATATTTCAAGTAGCA
GTATTGAGTATCACGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACAGAGGTACTTTATCAA
GACCCACAAGTTGGTACTGCCGTTGATGGTACAGTGATTCTCTATGTTTCAGTTGTAACTGAGAGTTCAAGCATTCAACA
GTCAAGCTCAGCAAGTACGACACATTCGTCGTCATCTACAAGTTCTAGTTCTGAAAGTACAGCTTCTAGTACCGAAACAG
CTACTGAAGCTACCCACACAGAGCAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(508-577)

PASTA domain (PASTA)

(436-502)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

91.738

93.408

0.857
  pknB Streptococcus mutans UA159

65.441

87.46

0.572
  stkP Streptococcus pneumoniae TIGR4

58.502

79.421

0.465
  stkP Streptococcus pneumoniae D39

58.3

79.421

0.463
  stkP Streptococcus pneumoniae R6

58.3

79.421

0.463
  stkP Streptococcus pneumoniae Rx1

58.097

79.421

0.461

Multiple sequence alignment