Detailed information NTG1111459

Bioinformatically predicted

Overview

• Name: micA
• Type: Regulator
• Locus tag: ACN076_RS07180
• Genome accession: NZ_CP184836
• Coordinates: 1462964..1463671 (-)
• Length: 235 a.a.
• NCBI ID: WP_261024623.1
• Uniprot ID: -
• Organism: Streptococcus sp. K0074
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1457964..1468671

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN076_RS07150 (ACN076_07150)	-	1458072..1458320 (+)	249	WP_420789700.1	DUF3173 family protein	-
ACN076_RS07155 (ACN076_07155)	-	1458322..1459473 (+)	1152	WP_420789701.1	tyrosine-type recombinase/integrase	-
ACN076_RS07160 (ACN076_07160)	-	1459544..1459843 (+)	300	WP_203176279.1	YbaB/EbfC family nucleoid-associated protein	-
ACN076_RS07165 (ACN076_07165)	-	1459953..1460726 (-)	774	WP_203176280.1	potassium channel family protein	-
ACN076_RS07170 (ACN076_07170)	vicX	1460811..1461620 (-)	810	WP_000004964.1	MBL fold metallo-hydrolase	Regulator
ACN076_RS07175 (ACN076_07175)	micB	1461622..1462971 (-)	1350	WP_420789702.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ACN076_RS07180 (ACN076_07180)	micA	1462964..1463671 (-)	708	WP_261024623.1	response regulator YycF	Regulator
ACN076_RS07185 (ACN076_07185)	mutY	1463727..1464902 (-)	1176	WP_420789703.1	A/G-specific adenine glycosylase	-
ACN076_RS07190 (ACN076_07190)	-	1465215..1465490 (-)	276	WP_049535169.1	HU family DNA-binding protein	-
ACN076_RS07195 (ACN076_07195)	-	1465598..1466437 (-)	840	WP_420789704.1	DegV family protein	-
ACN076_RS07200 (ACN076_07200)	-	1466578..1467426 (+)	849	WP_420789705.1	YitT family protein	-
ACN076_RS07205 (ACN076_07205)	-	1467514..1468431 (-)	918	WP_261127648.1	bifunctional riboflavin kinase/FAD synthetase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27095.80 Da
• Isoelectric Point: 4.5600

>NTDB_id=1111459 ACN076_RS07180 WP_261024623.1 1462964..1463671(-) (micA) [Streptococcus sp. K0074]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLTSVDNQESDENKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide

• Length: 708 bp

>NTDB_id=1111459 ACN076_RS07180 WP_261024623.1 1462964..1463671(-) (micA) [Streptococcus sp. K0074]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCACTAGAACAATTTGAAGCAGAGCAGCCAGATATTATTATTCTGGATTTGA
TGCTTCCCGAAATTGATGGTTTAGAAGTTGCTAAGACTATTCGCAAGACCAGTAGTGTACCTATTATCATGCTTTCAGCG
AAAGACAGTGAATTTGATAAGGTTATCGGTTTGGAGCTTGGTGCGGATGACTATGTGACCAAACCCTTCTCAAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTCCTTCGTCGTACAGATTTGACTTCTGTAGATAATCAAGAATCAGATGAAAATAAAA
CTCAACCCTTGCAAATTGGGGACTTGGAGATTGTTCCAGATGCCTATGTTGCTAAGAAATACGGTGAAGAACTAGACTTA
ACTCACCGTGAATTTGAGCTTTTGTACCACTTGGCTTCTCATATCGGTCAAGTAATTACGCGTGAACACTTGCTTGAAAC
GGTATGGGGGTATGATTATTTCGGAGATGTTCGAACAGTTGACGTAACTATCAGACGTTTGCGTGAGAAGATTGAAGACA
CACCAAGTCGTCCGGAGTATATTCTAACACGTCGCGGTGTTGGTTATTATATGAGAAATAATGATTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micA	Streptococcus pneumoniae Cp1015	94.017	99.574	0.936
vicR	Streptococcus mutans UA159	77.447	100	0.774
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
covR	Streptococcus salivarius strain HSISS4	44.589	98.298	0.438
scnR	Streptococcus mutans UA159	38.034	99.574	0.379