Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ACN076_RS07175 Genome accession   NZ_CP184836
Coordinates   1461622..1462971 (-) Length   449 a.a.
NCBI ID   WP_420789702.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1456622..1467971
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS07145 (ACN076_07145) - 1456899..1458071 (+) 1173 WP_420789699.1 Rep family protein -
  ACN076_RS07150 (ACN076_07150) - 1458072..1458320 (+) 249 WP_420789700.1 DUF3173 family protein -
  ACN076_RS07155 (ACN076_07155) - 1458322..1459473 (+) 1152 WP_420789701.1 tyrosine-type recombinase/integrase -
  ACN076_RS07160 (ACN076_07160) - 1459544..1459843 (+) 300 WP_203176279.1 YbaB/EbfC family nucleoid-associated protein -
  ACN076_RS07165 (ACN076_07165) - 1459953..1460726 (-) 774 WP_203176280.1 potassium channel family protein -
  ACN076_RS07170 (ACN076_07170) vicX 1460811..1461620 (-) 810 WP_000004964.1 MBL fold metallo-hydrolase Regulator
  ACN076_RS07175 (ACN076_07175) micB 1461622..1462971 (-) 1350 WP_420789702.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACN076_RS07180 (ACN076_07180) micA 1462964..1463671 (-) 708 WP_261024623.1 response regulator YycF Regulator
  ACN076_RS07185 (ACN076_07185) mutY 1463727..1464902 (-) 1176 WP_420789703.1 A/G-specific adenine glycosylase -
  ACN076_RS07190 (ACN076_07190) - 1465215..1465490 (-) 276 WP_049535169.1 HU family DNA-binding protein -
  ACN076_RS07195 (ACN076_07195) - 1465598..1466437 (-) 840 WP_420789704.1 DegV family protein -
  ACN076_RS07200 (ACN076_07200) - 1466578..1467426 (+) 849 WP_420789705.1 YitT family protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51390.88 Da        Isoelectric Point: 4.7226

>NTDB_id=1111458 ACN076_RS07175 WP_420789702.1 1461622..1462971(-) (micB) [Streptococcus sp. K0074]
MIKLIKDTVLTSDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKVKDLIAGDYSQVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGKITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LIIDSQDANGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMRGPDEEKKYDLVRDYPITSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVTMKTTDDQMILSISDQGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LAIAKEIVKQHEGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1111458 ACN076_RS07175 WP_420789702.1 1461622..1462971(-) (micB) [Streptococcus sp. K0074]
ATGATTAAACTAATTAAAGACACAGTTTTAACCAGTGATTTTATCTTTATCCTCATTCTACTTGGCTTTATTTTAGTCGT
GACCTTGCTTTTACTAGAAAATCGTCGGGATAATATTCGGTTGAAGCAAATCAATCAAAAGGTAAAAGACCTGATTGCAG
GAGATTATTCTCAGGTATTGGATATGCAGGGAAGCTCTGAAATCACCAATATTACCAATAATCTCAATGATTTATCAGAA
GTAATTCGTTTAACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTACATAGTATCCTCTCTTATATGACGGACGGAGT
CCTTGCGACCAATCGTCGTGGCAAGATTACCATGATTAATGACATGGCTAAGAAACAGTTAGGTGTTCAGAAAGAAGATG
TTCTCAACAAGAGTATCCTAGAGTTGCTTAAGATTGAAGATGAGTATGAACTTCGTGATTTGATTACCCAAATTCCTGAA
CTCATCATTGATTCTCAGGATGCTAATGGTGAGTATCTGAGCCTTCGTGTTCGCTTTGCCTTGATTCGTCGAGAGTCTGG
CTTTATCTCTGGTCTGGTTGCTGTTTTACACGATACGACGGAGCAGGAGAAGGAAGAGCGCGAACGGAGGCTCTTTGTTT
CCAACGTTAGTCATGAGCTACGTACTCCTCTAACTAGTGTGAAATCTTATCTTGAAGCCTTGGATGAAGGAGCATTATCA
GAACCTGTTGCACCAGACTTTATCAAGGTCTCTCTAGACGAAACTAACCGTATGATGCGGATGGTGACAGACCTTCTCCA
TCTTTCACGTATTGATAATGCAACCAGTCATTTGGATGTAGAGCTGATTAATTTCACTGCTTTTATTACCTTTATTCTTA
ACCGTTTTGATAAGATGAGGGGACCAGATGAAGAGAAGAAATATGATTTGGTAAGGGATTATCCGATTACTTCAGTCTGG
ATAGAGATTGATACAGATAAAATGACACAGGTGATTGACAACATTCTTAACAATGCTATTAAGTATTCTCCAGATGGTGG
GAAAATTACAGTGACCATGAAGACAACCGATGATCAGATGATTTTATCCATCTCAGACCAAGGATTGGGTATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTTTATCGTGTGGATCGCGCTAGAAGTCGTGCCCAAGGTGGTACGGGTCTAGGA
CTAGCAATTGCTAAAGAAATTGTCAAACAACATGAGGGCTTTATTTGGGCTAAGAGTGAATACGGTAAGGGATCAACCTT
CACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

90.205

97.773

0.882
  vicK Streptococcus mutans UA159

72.139

89.532

0.646

Multiple sequence alignment