Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ACN076_RS00995 Genome accession   NZ_CP184836
Coordinates   176845..178194 (-) Length   449 a.a.
NCBI ID   WP_420789988.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 171845..183194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS00985 (ACN076_00985) - 172175..175900 (-) 3726 WP_420789986.1 phosphoribosylformylglycinamidine synthase -
  ACN076_RS00990 (ACN076_00990) purC 175968..176675 (-) 708 WP_420789987.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  ACN076_RS00995 (ACN076_00995) comB 176845..178194 (-) 1350 WP_420789988.1 competence pheromone export protein ComB Regulator
  ACN076_RS01000 (ACN076_01000) comA 178207..180360 (-) 2154 WP_420789989.1 peptide cleavage/export ABC transporter ComA Regulator
  ACN076_RS01005 (ACN076_01005) - 180662..180850 (-) 189 WP_000757184.1 hypothetical protein -
  ACN076_RS01010 (ACN076_01010) - 181509..181724 (-) 216 WP_080673747.1 bacteriocin immunity protein -
  ACN076_RS01015 (ACN076_01015) - 181728..181883 (-) 156 WP_000357248.1 smi_0061 family bacteriocin-like peptide -
  ACN076_RS01020 (ACN076_01020) - 182097..182294 (-) 198 WP_000180818.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACN076_RS01025 (ACN076_01025) - 182328..182483 (-) 156 WP_049499436.1 hypothetical protein -
  ACN076_RS01030 (ACN076_01030) - 182494..182622 (-) 129 WP_049499438.1 smi_0059.1 family bacteriocin-like peptide -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49772.83 Da        Isoelectric Point: 6.2808

>NTDB_id=1111415 ACN076_RS00995 WP_420789988.1 176845..178194(-) (comB) [Streptococcus sp. K0074]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATFAEKEMSLSTRATVEPSRILANIQSTSNNRMLVNHLEENKL
VKKGELLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQVEIGNLISQTEAKIRDYQTAKSAIETGASLASQNLAYSLYQSYKSQGEENPQAKAQAVAQVEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLDQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSTMVAEGAILAQLYPSLEKEGKAKLTAYLSSKDVARIKVGDSVRYTTIHDAKNQLFLDSTITSIDATATKTEK
GNFFKIEAKTNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1111415 ACN076_RS00995 WP_420789988.1 176845..178194(-) (comB) [Streptococcus sp. K0074]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTCCCCAT
GTCCCTTCTGCTCGTGTTTTTGCTTGGATTTGCAACATTTGCAGAGAAGGAGATGAGTTTGTCTACTAGAGCTACTGTTG
AGCCTAGTCGAATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATGCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAAAAGGGAGAACTGTTAGTTCAATATCAGGAAGGGGCAGAGGGTGTCCAAGCGGAGTCTTATGCCAGTCAGTTGGA
CATGCTCAAGGATCAAAAAAAGCAATTGGAGTATTTGCAGAAGAGCTTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCATCCCAGAATGCAGCAGCTAGCCAAACCCAAGTCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTATTCTCTCT
ACCAGTCCTACAAGTCTCAGGGTGAGGAAAATCCGCAAGCTAAAGCTCAGGCAGTTGCGCAGGTTGAAGCGCAGCTTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGCTTAAG
CAGTCAATTGGAGTCTCTCAAATCCCAACACTTGGCTAAGGTTGGTCAGGAATTGACCCTTCTAGACCAGAAAATTTTGG
AGGCAGAATCGGGTAAGAAGGTTCAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGATTCTACCATGGTAGCAGAAGGTGCCATACTAGCCCAACTCTATCCGTCCTTGGAGAAAGA
AGGGAAAGCTAAACTCACAGCCTATCTTAGTTCAAAGGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACGA
CGATTCATGATGCTAAGAATCAACTTTTCCTAGATTCTACTATTACCAGCATCGATGCGACAGCTACCAAGACTGAAAAA
GGGAATTTCTTTAAAATTGAGGCGAAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTCGGTACGGGGTGGAAGGTCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

96.652

99.777

0.964
  comB Streptococcus pneumoniae TIGR4

95.759

99.777

0.955
  comB Streptococcus pneumoniae D39

95.536

99.777

0.953
  comB Streptococcus mitis NCTC 12261

95.536

99.777

0.953
  comB Streptococcus pneumoniae R6

95.536

99.777

0.953
  comB Streptococcus pneumoniae Rx1

95.536

99.777

0.953
  comB Streptococcus gordonii str. Challis substr. CH1

55.31

100

0.557

Multiple sequence alignment