Detailed information NTG1110972

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACNR93_RS08345
• Genome accession: NZ_CP184736
• Coordinates: 1688021..1690168 (+)
• Length: 715 a.a.
• NCBI ID: WP_420543565.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NM-2-29
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1683021..1695168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNR93_RS08310 (ACNR93_08310)	comD/comD1	1683113..1684387 (-)	1275	WP_420543562.1	sensor histidine kinase	Regulator
ACNR93_RS08315 (ACNR93_08315)	comE/comE1	1684446..1685177 (-)	732	WP_420543563.1	response regulator transcription factor	Regulator
ACNR93_RS08320 (ACNR93_08320)	-	1685536..1685781 (-)	246	WP_074483823.1	DUF3884 family protein	-
ACNR93_RS08325 (ACNR93_08325)	-	1685857..1686081 (-)	225	WP_094140014.1	helix-turn-helix domain-containing protein	-
ACNR93_RS08330 (ACNR93_08330)	-	1686071..1687072 (-)	1002	WP_420543564.1	thioredoxin fold domain-containing protein	-
ACNR93_RS08335 (ACNR93_08335)	-	1687233..1687535 (-)	303	WP_039697854.1	bacteriocin immunity protein	-
ACNR93_RS08340 (ACNR93_08340)	-	1687547..1687786 (-)	240	WP_074615778.1	garvicin Q family class II bacteriocin	-
ACNR93_RS08345 (ACNR93_08345)	comA/nlmT	1688021..1690168 (+)	2148	WP_420543565.1	peptide cleavage/export ABC transporter	Regulator
ACNR93_RS08350 (ACNR93_08350)	-	1690178..1691557 (+)	1380	WP_420543566.1	bacteriocin secretion accessory protein	-
ACNR93_RS08355 (ACNR93_08355)	-	1692101..1692775 (-)	675	WP_420543567.1	CPBP family intramembrane glutamic endopeptidase	-
ACNR93_RS08360 (ACNR93_08360)	-	1692808..1693500 (-)	693	WP_234794538.1	CPBP family intramembrane glutamic endopeptidase	-
ACNR93_RS08365 (ACNR93_08365)	-	1693494..1693676 (-)	183	WP_420543568.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
ACNR93_RS08370 (ACNR93_08370)	rsmA	1694037..1694909 (-)	873	WP_021143191.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 79983.03 Da
• Isoelectric Point: 8.8168

>NTDB_id=1110972 ACNR93_RS08345 WP_420543565.1 1688021..1690168(+) (comA/nlmT) [Streptococcus equinus strain NM-2-29]
MWRYKYVSQIDMRDCGVAALASVAKHYGSHFSLAHLRELAKTSKEGTTALGIVEAAKKIGFETRAIQANMELFEIPDIPY
PCIVHVNKQGKLQHYYIVYKAKKDSLIIGDPDPSVGVIKMAKADFAKEWTGVAIFLAPAPTYKPHKDKKNGLSSFLPIIF
KQKALLTYIVLASLLVTIINIVGSYYLQGILDEYIPSQLQSTLNIVSIGLVVTYIMQQIMSFSQQYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSIFLDVSILIIVGSVLILQNAKLFFLTLVALPIYAIII
FAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEETRYRNIDSEFVGYLDKSFTLSKYEAIQTSLKQGAQLIL
NVAILWYGSHLVMTGKISVGQLITYNTLLSYFTNPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDNKEVFNNKDFLKG
DLVFDDVSYKYGFGRDTLSHIKLHIKKGEKVSLVGVSGSGKTTLAKMMVNFYSPNQGNITLGGYDYKTIDKKILRQHINY
LPQQSYVFSGSILENLTLGASDNITQEDIIKACEIAEIRSDIEAMPMAYHTELSDGAGLSGGQKQRLAIARALLTKAPVL
ILDEATSGLDVLTEKRVIHNLLSLSDKTIIFVAHRLSIAEQSDRVLVLDKGKIVEEGHHKQLMKNQGFYAQLFHH

Nucleotide

• Length: 2148 bp

>NTDB_id=1110972 ACNR93_RS08345 WP_420543565.1 1688021..1690168(+) (comA/nlmT) [Streptococcus equinus strain NM-2-29]
ATGTGGAGATATAAATACGTTAGTCAGATTGATATGAGAGATTGTGGGGTGGCTGCTCTTGCTTCGGTCGCTAAACACTA
TGGCTCGCACTTTTCGCTTGCTCACTTGAGAGAATTGGCTAAGACTAGTAAAGAAGGTACAACTGCTCTTGGAATCGTCG
AAGCGGCAAAGAAAATTGGTTTTGAAACACGCGCCATTCAGGCAAATATGGAACTTTTTGAAATACCAGATATTCCTTAT
CCCTGTATCGTCCATGTCAATAAGCAAGGCAAGTTACAACATTACTATATCGTCTACAAAGCCAAAAAAGATTCTCTAAT
CATCGGTGACCCCGACCCAAGCGTCGGTGTGATAAAAATGGCTAAAGCTGATTTCGCCAAGGAATGGACTGGTGTTGCCA
TCTTTCTAGCGCCAGCTCCTACATATAAACCACACAAAGATAAGAAAAATGGTTTGAGTAGTTTTTTGCCGATTATCTTC
AAGCAAAAAGCCCTCTTAACATACATCGTTCTTGCTAGCTTACTAGTAACGATTATCAATATTGTTGGTTCTTACTACCT
GCAAGGCATTTTAGATGAGTACATTCCAAGCCAGCTGCAATCTACACTCAACATTGTTTCCATCGGTCTGGTTGTCACTT
ATATCATGCAACAAATCATGAGTTTTTCACAACAATACTTACTGGTTGTTCTTAGTCAACGCTTGACTATCGATGTGATT
TTATCTTATATCCGTCATATTTTTGAATTGCCCATGTCATTTTTTGCGACAAGACGAACTGGGGAAGTTATTTCACGATT
TACCGACGCTAATTCTATTATCGACGCGCTTGCCTCAACTATTCTTTCTATCTTTTTAGATGTCAGTATTTTAATTATCG
TTGGAAGTGTTTTGATTCTGCAGAATGCTAAATTATTCTTTCTCACTCTAGTTGCTCTTCCAATCTATGCCATTATCATC
TTTGCTTTTATGAAGCCGTTTGAGCGTATGAACCATGACGTCATGCAAGCAAATTCCATGGTCAGCTCTGCTATTATTGA
AGATATCAACGGAATTGAAACCATCAAGTCACTCACTAGTGAAGAAACTCGCTATCGCAATATCGATAGTGAATTTGTTG
GTTATTTAGACAAAAGTTTCACTCTTAGTAAATATGAAGCAATCCAAACGTCATTAAAACAGGGAGCACAGCTGATTTTA
AACGTCGCTATTCTTTGGTACGGTTCACATCTAGTTATGACAGGGAAAATTTCTGTTGGGCAGTTGATTACCTACAACAC
TCTCTTATCTTACTTCACAAATCCGATGGAAAATATTATTAATTTACAGACTAAGTTGCAGTCAGCTAAAGTTGCCAATA
ATCGACTTAACGAAGTCTATCTCGTATCTTCTGAATTTGACAATAAAGAAGTCTTTAACAACAAAGACTTTCTCAAAGGT
GACCTTGTCTTTGATGATGTTTCTTATAAATACGGCTTTGGACGTGATACTCTTAGTCACATTAAACTTCATATCAAGAA
AGGTGAAAAAGTTAGCCTAGTCGGCGTTAGTGGCTCAGGTAAAACCACCCTTGCAAAAATGATGGTTAATTTTTACAGTC
CAAACCAAGGAAACATCACCCTAGGTGGTTATGATTATAAAACCATTGATAAAAAAATCCTTCGACAACATATCAACTAT
TTGCCTCAGCAATCTTATGTCTTCTCAGGAAGCATTTTAGAAAATCTAACCTTGGGAGCTTCTGACAATATCACACAGGA
AGATATTATCAAAGCTTGTGAAATTGCAGAAATTCGATCAGACATCGAAGCGATGCCGATGGCTTATCACACTGAACTTT
CAGACGGAGCTGGTTTATCAGGTGGTCAGAAACAGCGCCTTGCTATTGCGCGCGCTCTACTCACCAAAGCTCCTGTTTTG
ATTTTGGATGAAGCAACAAGTGGACTTGATGTGCTAACTGAAAAACGAGTTATCCACAATTTACTATCTCTGTCCGACAA
AACTATTATCTTCGTAGCCCATCGTTTGAGCATTGCAGAACAATCAGACCGTGTATTGGTGCTTGATAAGGGGAAAATCG
TTGAAGAAGGACATCACAAGCAACTTATGAAAAATCAAGGCTTTTATGCTCAACTATTTCATCATTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.769	100	0.708
comA	Streptococcus mitis NCTC 12261	67.042	99.301	0.666
comA	Streptococcus mitis SK321	66.62	99.301	0.662
comA	Streptococcus pneumoniae Rx1	66.808	99.021	0.662
comA	Streptococcus pneumoniae D39	66.808	99.021	0.662
comA	Streptococcus pneumoniae R6	66.808	99.021	0.662
comA	Streptococcus pneumoniae TIGR4	66.525	99.021	0.659
comA	Streptococcus gordonii str. Challis substr. CH1	65.113	99.021	0.645