Detailed information NTG1110971

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: ACNR93_RS08315
• Genome accession: NZ_CP184736
• Coordinates: 1684446..1685177 (-)
• Length: 243 a.a.
• NCBI ID: WP_420543563.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NM-2-29
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1679446..1690177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNR93_RS08280 (ACNR93_08280)	-	1679833..1680030 (-)	198	WP_126438119.1	hypothetical protein	-
ACNR93_RS08285 (ACNR93_08285)	-	1680191..1680484 (-)	294	WP_039697859.1	bacteriocin immunity protein	-
ACNR93_RS08290 (ACNR93_08290)	-	1680514..1680819 (-)	306	WP_420543558.1	bacteriocin immunity protein	-
ACNR93_RS08295 (ACNR93_08295)	-	1680839..1681126 (-)	288	WP_420543559.1	DUF3884 family protein	-
ACNR93_RS08300 (ACNR93_08300)	-	1681309..1682631 (-)	1323	WP_420543560.1	sensor histidine kinase	-
ACNR93_RS08305 (ACNR93_08305)	comC/comC1	1682945..1683097 (+)	153	WP_420543561.1	hypothetical protein	Regulator
ACNR93_RS08310 (ACNR93_08310)	comD/comD1	1683113..1684387 (-)	1275	WP_420543562.1	sensor histidine kinase	Regulator
ACNR93_RS08315 (ACNR93_08315)	comE/comE1	1684446..1685177 (-)	732	WP_420543563.1	response regulator transcription factor	Regulator
ACNR93_RS08320 (ACNR93_08320)	-	1685536..1685781 (-)	246	WP_074483823.1	DUF3884 family protein	-
ACNR93_RS08325 (ACNR93_08325)	-	1685857..1686081 (-)	225	WP_094140014.1	helix-turn-helix domain-containing protein	-
ACNR93_RS08330 (ACNR93_08330)	-	1686071..1687072 (-)	1002	WP_420543564.1	thioredoxin fold domain-containing protein	-
ACNR93_RS08335 (ACNR93_08335)	-	1687233..1687535 (-)	303	WP_039697854.1	bacteriocin immunity protein	-
ACNR93_RS08340 (ACNR93_08340)	-	1687547..1687786 (-)	240	WP_074615778.1	garvicin Q family class II bacteriocin	-
ACNR93_RS08345 (ACNR93_08345)	comA/nlmT	1688021..1690168 (+)	2148	WP_420543565.1	peptide cleavage/export ABC transporter	Regulator

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28140.01 Da
• Isoelectric Point: 5.9193

>NTDB_id=1110971 ACNR93_RS08315 WP_420543563.1 1684446..1685177(-) (comE/comE1) [Streptococcus equinus strain NM-2-29]
MLDIFILEDNITQQFRIERQIEAIMEKNNWAYQHLEAFAASEDIIARASEKKSHQIFFLDLEIKGDEKQGIDVARAIREK
DSTAIIAFVTTHSEFMLLTYQSLVGAIDFIDKNLNDAAFEQRLELCLKEALKHQKGNLGENSYLFETAKARIRVAYDDIL
YFETSPTVHRVILHTKTGQTEFYGTIAEVAKSDERLFKCHRSFVINVNNVTEFDKSTRTAYFENGSYCQVSRDKLKKLMA
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=1110971 ACNR93_RS08315 WP_420543563.1 1684446..1685177(-) (comE/comE1) [Streptococcus equinus strain NM-2-29]
ATGTTAGATATTTTTATCCTTGAGGATAATATCACGCAACAATTTCGTATTGAGCGACAGATAGAGGCAATTATGGAAAA
GAATAACTGGGCTTATCAGCACTTGGAAGCTTTTGCGGCATCTGAGGATATTATTGCAAGAGCATCTGAAAAGAAGAGCC
ATCAGATTTTCTTTCTTGATTTAGAAATTAAAGGGGATGAAAAGCAAGGAATTGACGTGGCAAGAGCCATCCGTGAGAAG
GATTCGACAGCTATTATTGCTTTTGTAACGACTCATTCTGAGTTTATGCTTTTAACTTATCAGTCGTTGGTTGGTGCGAT
TGATTTCATTGATAAAAATTTAAACGATGCAGCTTTTGAACAACGTCTAGAGTTATGCTTGAAGGAAGCTCTTAAGCATC
AAAAAGGAAATTTAGGTGAGAATTCTTACCTTTTTGAAACTGCCAAAGCGAGAATTCGTGTAGCTTACGATGATATTTTA
TATTTTGAAACATCGCCAACCGTCCACCGAGTGATTTTACACACAAAAACTGGTCAAACTGAATTTTACGGAACGATTGC
GGAGGTTGCCAAATCAGATGAACGTCTGTTCAAATGTCACCGCTCATTCGTGATTAATGTTAATAATGTCACTGAATTTG
ATAAAAGCACCCGAACAGCTTATTTCGAAAACGGCTCTTACTGCCAAGTCTCAAGAGACAAACTTAAAAAACTGATGGCA
GAAATGAGGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-240)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	87.654	100	0.877
comE/comE2	Streptococcus equinus JB1	47.521	99.588	0.473
comE/blpR	Streptococcus mutans UA159	47.303	99.177	0.469