Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   ACNR93_RS06785 Genome accession   NZ_CP184736
Coordinates   1376672..1377382 (-) Length   236 a.a.
NCBI ID   WP_021142846.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1371672..1382382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS06770 (ACNR93_06770) rnc 1373620..1374306 (-) 687 WP_021142842.1 ribonuclease III -
  ACNR93_RS06775 (ACNR93_06775) vicX 1374517..1375326 (-) 810 WP_021142843.1 MBL fold metallo-hydrolase Regulator
  ACNR93_RS06780 (ACNR93_06780) vicK 1375327..1376679 (-) 1353 WP_027968495.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACNR93_RS06785 (ACNR93_06785) vicR 1376672..1377382 (-) 711 WP_021142846.1 response regulator YycF Regulator
  ACNR93_RS06790 (ACNR93_06790) - 1377690..1378454 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  ACNR93_RS06795 (ACNR93_06795) - 1378465..1379268 (+) 804 WP_420543432.1 transporter substrate-binding domain-containing protein -
  ACNR93_RS06800 (ACNR93_06800) - 1379284..1379988 (+) 705 WP_004232799.1 amino acid ABC transporter permease -
  ACNR93_RS06805 (ACNR93_06805) - 1379998..1380645 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  ACNR93_RS06810 (ACNR93_06810) - 1380677..1381285 (-) 609 WP_134775509.1 TVP38/TMEM64 family protein -
  ACNR93_RS06815 (ACNR93_06815) - 1381503..1381799 (-) 297 WP_074668750.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27179.94 Da        Isoelectric Point: 4.6553

>NTDB_id=1110959 ACNR93_RS06785 WP_021142846.1 1376672..1377382(-) (vicR) [Streptococcus equinus strain NM-2-29]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIEKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1110959 ACNR93_RS06785 WP_021142846.1 1376672..1377382(-) (vicR) [Streptococcus equinus strain NM-2-29]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAATTTAACTAAAGAAGGTTATGA
AACCGTTACGGCTTTTGATGGTCGTGAAGCTATTGAAAAATTTGAAGAAGAAAATCCTGATTTGATTATTTTGGATTTGA
TGTTGCCAGAATTGGACGGACTTGAAGTCGCAAAAGAAGTTCGTAAAACAAGTCATATTCCTATTATTATGCTATCAGCA
AAAGATAGTGAATTTGATAAAGTTATCGGTCTTGAAATCGGTGCTGACGACTACGTGACAAAACCATTTTCAAACCGTGA
ATTGTTAGCGCGTGTCAAAGCGCATCTTCGCCGCACTGAAAATATCGAATCTGCAGTTGCTGAAGAAAATGCGTCTTCTT
CAAACTCAGAAATCACAATCGGTGACTTGAAAATCTTGCCTGATGCATTTGTGGCACAAAAACGTGGTGAAGACATTGAA
TTAACACACCGTGAGTTTGAATTGTTGCATCATTTGGCAACTCACATGGGACAAGTAATGACACGTGAATACCTTTTGGA
AACTGTCTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGACGTAACAATCCGTCGTTTACGTGAAAAAATCGAAG
ACACACCAAGTCGTCCAGAATATATTTTGACACGTCGTGGTGTTGGATATTACATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

78.632

99.153

0.78
  covR Streptococcus salivarius strain HSISS4

47.414

98.305

0.466
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

98.305

0.453
  scnR Streptococcus mutans UA159

36.864

100

0.369

Multiple sequence alignment