Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ACNR93_RS06780 Genome accession   NZ_CP184736
Coordinates   1375327..1376679 (-) Length   450 a.a.
NCBI ID   WP_027968495.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1370327..1381679
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS06770 (ACNR93_06770) rnc 1373620..1374306 (-) 687 WP_021142842.1 ribonuclease III -
  ACNR93_RS06775 (ACNR93_06775) vicX 1374517..1375326 (-) 810 WP_021142843.1 MBL fold metallo-hydrolase Regulator
  ACNR93_RS06780 (ACNR93_06780) vicK 1375327..1376679 (-) 1353 WP_027968495.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACNR93_RS06785 (ACNR93_06785) vicR 1376672..1377382 (-) 711 WP_021142846.1 response regulator YycF Regulator
  ACNR93_RS06790 (ACNR93_06790) - 1377690..1378454 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  ACNR93_RS06795 (ACNR93_06795) - 1378465..1379268 (+) 804 WP_420543432.1 transporter substrate-binding domain-containing protein -
  ACNR93_RS06800 (ACNR93_06800) - 1379284..1379988 (+) 705 WP_004232799.1 amino acid ABC transporter permease -
  ACNR93_RS06805 (ACNR93_06805) - 1379998..1380645 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  ACNR93_RS06810 (ACNR93_06810) - 1380677..1381285 (-) 609 WP_134775509.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51377.32 Da        Isoelectric Point: 4.7300

>NTDB_id=1110958 ACNR93_RS06780 WP_027968495.1 1375327..1376679(-) (vicK) [Streptococcus equinus strain NM-2-29]
MNNIMSQNQYLFEQAILFLLAFVAVYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQQQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1110958 ACNR93_RS06780 WP_027968495.1 1375327..1376679(-) (vicK) [Streptococcus equinus strain NM-2-29]
ATGAATAATATAATGTCACAGAATCAGTATCTGTTTGAGCAGGCAATCTTGTTTTTGCTCGCTTTTGTCGCTGTTTATTT
TATTCATTTAGCGATAAGAGATTATCGAACTTCAGTTAATATTCGTCGTTTGAGTGGTAAGGTTCGTGAGCTTATCACTG
GTAAATACACTGAAGACATCATTATTGAAAAAGATAGAGATTTGGCTGAACTTGCTGGTCAGTTAAATGACTTGTCAACG
GTTTTTCGCTTGGCTCAGGAAAATCTTGCGCAGGAAAAAAATCGTTTGGCTAGTATTTTGTCTTATATGACTGACGGTGT
CTTGGCTACTGACCGTTCTGGAAATATCACCATGATTAACCAGACAGCTCAGCAGCAACTTAATCTTGAACGCGAAGAAG
CTCTTGGAATGAATATTGTTGACATTCTTGGGGACGATAGCGATTATAGTTACCATGATTTGGTTTCTAAGACACCTGAG
ATTGTTCTAAATCGTCGTGATGAGACAGGTGAATTTATCACTTTGCGAATTCGTTTTGCGCTGAATCGTCGTGATAGTGG
CTTTATCTCAGGGTTAATTGCTGTTTTACATGATACAACGGAACAAGAAAAAGAAGACCGTGAACGTCGTTTATTCGTAT
CAAATGTTAGTCACGAATTGCGTACACCGTTGACATCTGTGAAATCATATTTGGAAGCTTTGGATGAAGGTGCACTTAAA
GAAGATATTGCACCAAGTTTTATTAAAGTTTCTCTTGATGAAACAAACCGTATGATTCGAATGATTTCTGATTTGCTCAA
TTTGTCTCGAATTGATAATCAGACTGTTCAGCTTGAAGTTGAAATGACTAACTTTACAGCATTTATGACATCAATTTTGA
ACCGTTTTGACCAAATTAAGAGTCAACATACAGTCGCTGGTAAGCAGTATGAGATTGTCAGAGATTATCCAATCAAGTCT
ATCTGGCTAGAAATTGACCCAGATAAAATGACGCAAGTTCTGGATAATATCCTTAATAATGCAATTAAGTATTCGCCAGA
TGGTGGTAAAATCACTGTCAGCATGAAGACGACTGAGACACAGTTGATTATTTCAATTTCTGATGAAGGTCTTGGTATTC
CTAAGAAAGATTTGCCGCTAATCTTTGACCGATTCTATCGTGTTGACAAGGCTAGAAGTCGTGCTCAAGGTGGTTCAGGA
CTTGGTCTTGCGATTGCAAAAGAAATTGTTAAACAACACAAAGGATTTATTTGGGCTCAAAGTACTTATGGAAAAGGCTC
AACCTTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGACGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.627

92.222

0.707
  micB Streptococcus pneumoniae Cp1015

66.038

94.222

0.622

Multiple sequence alignment