Detailed information NTG1110917

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ACNR93_RS00345
• Genome accession: NZ_CP184736
• Coordinates: 50679..51590 (+)
• Length: 303 a.a.
• NCBI ID: WP_420543656.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NM-2-29
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 45679..56590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNR93_RS00320 (ACNR93_00320)	purD	45822..47084 (+)	1263	WP_420543652.1	phosphoribosylamine--glycine ligase	-
ACNR93_RS00325 (ACNR93_00325)	-	47074..47523 (+)	450	WP_420543653.1	DUF523 domain-containing protein	-
ACNR93_RS00330 (ACNR93_00330)	purE	47523..48011 (+)	489	WP_420543654.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
ACNR93_RS00335 (ACNR93_00335)	purK	47998..49089 (+)	1092	WP_420543655.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
ACNR93_RS00340 (ACNR93_00340)	purB	49230..50528 (+)	1299	WP_166043588.1	adenylosuccinate lyase	-
ACNR93_RS00345 (ACNR93_00345)	comR	50679..51590 (+)	912	WP_420543656.1	helix-turn-helix domain-containing protein	Regulator
ACNR93_RS00350 (ACNR93_00350)	ruvB	51761..52759 (+)	999	WP_021141399.1	Holliday junction branch migration DNA helicase RuvB	-
ACNR93_RS00355 (ACNR93_00355)	-	52969..53400 (+)	432	WP_021141400.1	low molecular weight protein-tyrosine-phosphatase	-
ACNR93_RS00360 (ACNR93_00360)	-	53417..53797 (+)	381	WP_074451189.1	MORN repeat-containing protein	-
ACNR93_RS00365 (ACNR93_00365)	-	53794..55587 (+)	1794	WP_420543657.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35582.89 Da
• Isoelectric Point: 4.7069

>NTDB_id=1110917 ACNR93_RS00345 WP_420543656.1 50679..51590(+) (comR) [Streptococcus equinus strain NM-2-29]
MEVKKFGNKIRILREKKGISREEFCGDETELSVRQLARIELNQSIPNLSKVQFIANRLGVRLGTLTDGDSLELPKRYKEL
KYLILRTPTYKDEKRVNLRDSYFDEIYSDFYEDLPEEEQLIVECMRSKADVFLTDNSNLATKLLEDYFYQTKSKSHYSIN
DLIIIDLYMVCANASNYEYFMFDKDEFIGIAKNLLEQENHFSLAEIFVLNNILFGSLSLLVDLKMWDEVELTLDVLKGIM
AKIQDFHKKPVLNMIEWKYILERFGQTEKAQKLYEEAVLYANLIGDVYLANKITEEWIKDTTA

Nucleotide

• Length: 912 bp

>NTDB_id=1110917 ACNR93_RS00345 WP_420543656.1 50679..51590(+) (comR) [Streptococcus equinus strain NM-2-29]
ATGGAAGTGAAAAAATTTGGGAACAAAATTCGTATTTTGCGGGAGAAAAAGGGAATCTCACGCGAAGAATTCTGTGGGGA
CGAGACCGAATTATCCGTACGACAACTAGCACGAATTGAGCTAAATCAATCGATACCTAACCTAAGTAAAGTCCAATTCA
TTGCTAATCGCCTTGGCGTAAGACTTGGAACCCTGACAGACGGCGATAGCCTAGAATTACCAAAGCGGTATAAAGAGCTG
AAGTATTTAATTTTGCGTACGCCAACGTATAAAGATGAAAAGCGTGTGAATTTAAGAGATTCTTATTTTGATGAGATTTA
CTCTGACTTTTACGAAGACCTTCCTGAGGAGGAGCAATTAATCGTGGAGTGCATGCGCTCAAAAGCAGATGTCTTTTTAA
CTGATAATAGTAATTTAGCCACAAAGTTGTTAGAAGACTATTTTTATCAAACAAAATCAAAATCACATTATTCGATTAAT
GACTTAATCATAATTGATTTATATATGGTTTGTGCAAATGCTTCAAATTATGAATATTTTATGTTTGATAAAGATGAATT
TATTGGTATAGCTAAGAATCTATTAGAACAAGAAAATCACTTTTCGCTAGCAGAAATTTTTGTCTTAAATAATATTTTAT
TTGGTAGTTTGAGCTTGTTGGTTGATTTAAAAATGTGGGACGAAGTGGAATTGACTTTAGATGTTTTAAAAGGAATTATG
GCTAAAATTCAAGATTTTCATAAGAAGCCAGTTTTGAATATGATTGAGTGGAAGTATATTTTGGAACGTTTTGGTCAAAC
AGAAAAGGCTCAAAAATTATATGAAGAGGCAGTGTTATATGCAAATTTGATAGGTGATGTTTATTTAGCTAATAAAATAA
CAGAAGAATGGATAAAAGATACAACAGCATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (10-63)

• ComR tetratricopeptide (ComR_TPR) (74-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.203	96.04	0.492
comR	Streptococcus pyogenes MGAS8232	46.844	99.34	0.465
comR	Streptococcus pyogenes MGAS315	46.309	98.35	0.455
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus suis P1/7	39.394	98.02	0.386
comR	Streptococcus suis 05ZYH33	39.394	98.02	0.386
comR	Streptococcus suis D9	37.097	100	0.38