Detailed information NTG1105918

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: V3C22_RS00350
• Genome accession: NZ_CP183775
• Coordinates: 58243..59157 (+)
• Length: 304 a.a.
• NCBI ID: WP_226707036.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain Xc
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 53243..64157

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V3C22_RS00325 (V3C22_00325)	-	53778..54203 (+)	426	WP_002302028.1	SRPBCC family protein	-
V3C22_RS00330 (V3C22_00330)	-	54307..54885 (+)	579	WP_023470478.1	hypothetical protein	-
V3C22_RS00335 (V3C22_00335)	-	54905..55630 (+)	726	WP_226708929.1	hypothetical protein	-
V3C22_RS00340 (V3C22_00340)	purB	55854..57152 (+)	1299	WP_226707034.1	adenylosuccinate lyase	-
V3C22_RS00345 (V3C22_00345)	-	57172..57858 (+)	687	WP_024782542.1	DNA alkylation repair protein	-
V3C22_RS00350 (V3C22_00350)	comR	58243..59157 (+)	915	WP_226707036.1	helix-turn-helix domain-containing protein	Regulator
V3C22_RS00355 (V3C22_00355)	-	59689..61533 (-)	1845	WP_226707038.1	carbohydrate-binding domain-containing protein	-
V3C22_RS00360 (V3C22_00360)	ruvB	61869..62864 (+)	996	WP_002269367.1	Holliday junction branch migration DNA helicase RuvB	-
V3C22_RS00365 (V3C22_00365)	-	62902..63327 (+)	426	WP_002303978.1	low molecular weight protein-tyrosine-phosphatase	-
V3C22_RS00370 (V3C22_00370)	-	63392..63775 (+)	384	WP_226707040.1	hypothetical protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35255.41 Da
• Isoelectric Point: 5.1266

>NTDB_id=1105918 V3C22_RS00350 WP_226707036.1 58243..59157(+) (comR) [Streptococcus mutans strain Xc]
MLKDFGKKIKSLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSMPTLNKAVYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVHCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAEAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide

• Length: 915 bp

>NTDB_id=1105918 V3C22_RS00350 WP_226707036.1 58243..59157(+) (comR) [Streptococcus mutans strain Xc]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAGCCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCTTGATGA
ATCTCAATTGTCAACACGGCAGCTGACTAGAATTGAATCAGGACAGTCTATGCCAACTCTTAATAAAGCTGTTTATATTG
CAGGACGTTTAGGAGTGACGCTTGGCTATTTAACGGACGGAGAAAATGTTGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGCGACCAGCAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTCGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACTAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAAACATTGCTTAAACAGGTACATTGTCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTAA
ATAATTTTGGACTTCTCTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTCAGCAATAAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GGAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (9-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	99.013	100	0.99
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	53.125	94.737	0.503
comR	Streptococcus pyogenes MGAS8232	46.689	99.342	0.464
comR	Streptococcus pyogenes MGAS315	47.157	98.355	0.464
comR	Streptococcus suis P1/7	43.813	98.355	0.431
comR	Streptococcus suis 05ZYH33	43.813	98.355	0.431
comR	Streptococcus suis D9	37	98.684	0.365