Detailed information NTG0109773

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ABXG87_RS01440
• Genome accession: NZ_AP031488
• Coordinates: 270437..272533 (+)
• Length: 698 a.a.
• NCBI ID: WP_073686724.1
• Uniprot ID: A0AAX1YC69
• Organism: Streptococcus salivarius strain NBRC 13956
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 265437..277533

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABXG87_RS01415 (Ssa13956_02260)	trkA	265528..266877 (-)	1350	WP_013990035.1	Trk system potassium transporter TrkA	-
ABXG87_RS01420 (Ssa13956_02270)	-	267155..267664 (+)	510	WP_070578732.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
ABXG87_RS01425 (Ssa13956_02280)	-	267973..268530 (+)	558	WP_013990037.1	ECF transporter S component	-
ABXG87_RS01430 (Ssa13956_02290)	-	268533..269183 (+)	651	WP_353551696.1	phosphatase PAP2 family protein	-
ABXG87_RS01435 (Ssa13956_02300)	comR	269363..270262 (+)	900	WP_045768781.1	helix-turn-helix transcriptional regulator	Regulator
ABXG87_RS01440 (Ssa13956_02310)	comA	270437..272533 (+)	2097	WP_073686724.1	peptide cleavage/export ABC transporter	Regulator
ABXG87_RS01445 (Ssa13956_02320)	-	272643..272975 (+)	333	WP_013990041.1	DUF805 domain-containing protein	-
ABXG87_RS01450 (Ssa13956_02330)	-	273027..273743 (-)	717	WP_201710510.1	hypothetical protein	-
ABXG87_RS01455 (Ssa13956_02340)	-	274151..274666 (+)	516	WP_002886548.1	AmiS/UreI family transporter	-
ABXG87_RS01460 (Ssa13956_02350)	-	274691..274993 (+)	303	WP_002886558.1	urease subunit gamma	-
ABXG87_RS01465 (Ssa13956_02360)	-	275005..275316 (+)	312	WP_002886559.1	urease subunit beta	-
ABXG87_RS01470 (Ssa13956_02370)	ureC	275332..277050 (+)	1719	WP_002886560.1	urease subunit alpha	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 78497.42 Da
• Isoelectric Point: 8.9594

>NTDB_id=109773 ABXG87_RS01440 WP_073686724.1 270437..272533(+) (comA) [Streptococcus salivarius strain NBRC 13956]
MSKYPYISQIDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEEGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGYEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILVFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide

• Length: 2097 bp

>NTDB_id=109773 ABXG87_RS01440 WP_073686724.1 270437..272533(+) (comA) [Streptococcus salivarius strain NBRC 13956]
ATGTCAAAATATCCATATATTTCACAGATTGATCAGCGTGATTGTGGTGTCGCTGCCTTAGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGATTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACAGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCGATTTTGTTC
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTAGTTAATATCATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTAACCATGATTTCACTGGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGAAATTACTTATCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCTTGCCTATTAGTTTCTTTAGTTCACGTCGCACTGGTGAAATCACGTCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTT
TAGCTGTGGCCCTTATTTTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTTCCTCTTTATGTGTTAATCATT
TTGGCCTTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAAAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACTTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCCAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAGAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTCTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACAACCTTAGCGAAAATGTTGTCAGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTAGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACAGGAACCATTTTAGAAAATCTGCTATTAGGATATGAAGGAGAAGTTGATGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAAGACGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCCAAGCAGCCTATCTTGGTTTTTGACGAAGCTACCAGT
GGTCTTGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (3-139)

• ABC transporter transmembrane region (ABC_membrane) (167-436)

• ABC transporter (ABC_tran) (494-640)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	53.305	99.713	0.532
comA	Streptococcus mitis SK321	53.69	98.997	0.532
comA	Streptococcus mitis NCTC 12261	53.256	98.997	0.527
comA	Streptococcus pneumoniae Rx1	53.111	98.997	0.526
comA	Streptococcus pneumoniae D39	53.111	98.997	0.526
comA	Streptococcus pneumoniae R6	53.111	98.997	0.526
comA	Streptococcus pneumoniae TIGR4	52.967	98.997	0.524
comA/nlmT	Streptococcus mutans UA159	50.29	98.854	0.497