Detailed information NTG0109608

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: ACGHT2_RS03205
• Genome accession: NZ_AP031455
• Coordinates: 579744..580409 (+)
• Length: 221 a.a.
• NCBI ID: WP_048791496.1
• Uniprot ID: A0AAW6YB25
• Organism: Streptococcus pasteurianus strain k46-0107-A9
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 574744..585409

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACGHT2_RS03175 (K460107A9_05480)	-	574819..575997 (+)	1179	WP_048791494.1	MFS transporter	-
ACGHT2_RS03180 (K460107A9_05490)	-	576052..576912 (+)	861	WP_048791495.1	helix-turn-helix transcriptional regulator	-
ACGHT2_RS03185 (K460107A9_05500)	-	576917..577546 (+)	630	WP_048791504.1	ROK family protein	-
ACGHT2_RS03190 (K460107A9_05520)	-	577778..578059 (-)	282	WP_003063819.1	GIY-YIG nuclease family protein	-
ACGHT2_RS03195 (K460107A9_05530)	-	578034..578795 (-)	762	WP_003063822.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
ACGHT2_RS03200 (K460107A9_05540)	-	578903..579649 (+)	747	WP_003063827.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
ACGHT2_RS03205 (K460107A9_05550)	comEA	579744..580409 (+)	666	WP_048791496.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACGHT2_RS03210 (K460107A9_05560)	comEC/celB	580402..582633 (+)	2232	WP_390578450.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACGHT2_RS03215 (K460107A9_05570)	holA	582706..583743 (+)	1038	WP_043910377.1	DNA polymerase III subunit delta	-
ACGHT2_RS03220 (K460107A9_05580)	sodA	583832..584440 (+)	609	WP_013851603.1	superoxide dismutase SodA	-
ACGHT2_RS03225 (K460107A9_05590)	-	584589..585314 (+)	726	WP_003063840.1	YebC/PmpR family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 23615.37 Da
• Isoelectric Point: 4.2822

>NTDB_id=109608 ACGHT2_RS03205 WP_048791496.1 579744..580409(+) (comEA) [Streptococcus pasteurianus strain k46-0107-A9]
MIEEIKEKLLENKTLAAVLGIILVMIIGFFAWLNVTKTTADAQNDLPALSTTFSTSSSASDLKTERSSSQTETQKMFVDI
KGAVKNEGVYELSNGSRVTDVVKLAGGFTEDADKKSVNLAEKVTDESVIYVARVDENVAPATTNSQANGSAQQEESSDKI
NLNTATLAELQTISGIGAKRAQDIIDYRDANGGFSSVDDLANVSGIGEKILEKLKSEVTVD

Nucleotide

• Length: 666 bp

>NTDB_id=109608 ACGHT2_RS03205 WP_048791496.1 579744..580409(+) (comEA) [Streptococcus pasteurianus strain k46-0107-A9]
ATGATTGAAGAAATAAAAGAAAAACTTTTGGAGAACAAAACGTTGGCAGCGGTATTGGGGATAATACTTGTCATGATAAT
CGGATTTTTTGCTTGGTTAAATGTGACAAAAACAACAGCGGATGCGCAAAATGACCTACCTGCCCTAAGCACGACTTTTT
CGACAAGTAGTAGCGCAAGTGATTTAAAAACAGAACGTTCAAGTTCGCAAACTGAGACTCAAAAAATGTTTGTAGATATC
AAAGGTGCTGTGAAAAATGAGGGGGTTTATGAGCTTTCAAACGGTAGCCGTGTGACAGATGTGGTCAAATTAGCAGGTGG
TTTTACAGAAGATGCTGATAAGAAGTCGGTGAATCTGGCTGAAAAAGTAACCGATGAATCGGTGATTTATGTGGCAAGAG
TTGATGAAAATGTTGCTCCTGCAACGACTAATTCACAAGCAAATGGCAGCGCTCAACAGGAAGAAAGTTCAGATAAAATC
AACCTTAATACCGCAACTTTGGCGGAACTCCAGACGATTTCTGGCATTGGCGCCAAACGTGCCCAAGATATTATTGACTA
CCGTGATGCTAATGGTGGTTTTTCATCAGTTGATGACTTAGCGAATGTGTCTGGTATCGGAGAAAAAATACTAGAAAAGC
TAAAATCTGAGGTGACCGTTGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (157-219)

• SLBB domain (SLBB) (78-131)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	46.862	100	0.507
comEA/celA/cilE	Streptococcus mitis SK321	45.701	100	0.457
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	44.091	99.548	0.439
comEA/celA/cilE	Streptococcus mitis NCTC 12261	43.439	100	0.434
comEA/celA/cilE	Streptococcus pneumoniae Rx1	43.182	99.548	0.43
comEA/celA/cilE	Streptococcus pneumoniae D39	43.182	99.548	0.43
comEA/celA/cilE	Streptococcus pneumoniae R6	43.182	99.548	0.43
comEA	Latilactobacillus sakei subsp. sakei 23K	37.5	100	0.38