Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACMHDP_RS07330 Genome accession   NZ_CP180195
Coordinates   1434863..1436152 (+) Length   429 a.a.
NCBI ID   WP_414840690.1    Uniprot ID   -
Organism   Enterococcus saccharolyticus strain GXN23C125Es     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1429863..1441152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMHDP_RS07315 (ACMHDP_07315) - 1430096..1431067 (-) 972 Protein_1427 IS30 family transposase -
  ACMHDP_RS07320 (ACMHDP_07320) - 1431418..1433319 (+) 1902 WP_414840688.1 diguanylate cyclase -
  ACMHDP_RS07325 (ACMHDP_07325) rlmH 1434095..1434574 (-) 480 WP_414840689.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACMHDP_RS07330 (ACMHDP_07330) htrA 1434863..1436152 (+) 1290 WP_414840690.1 S1C family serine protease Regulator
  ACMHDP_RS07335 (ACMHDP_07335) ytpR 1436194..1436805 (-) 612 WP_016175964.1 YtpR family tRNA-binding protein -
  ACMHDP_RS07340 (ACMHDP_07340) - 1437173..1437637 (-) 465 WP_016175965.1 universal stress protein -
  ACMHDP_RS07345 (ACMHDP_07345) - 1437662..1437973 (-) 312 WP_016175966.1 thioredoxin family protein -
  ACMHDP_RS07350 (ACMHDP_07350) pepA 1438072..1439148 (-) 1077 WP_016175967.1 glutamyl aminopeptidase -
  ACMHDP_RS07355 (ACMHDP_07355) - 1439278..1439616 (+) 339 WP_016175968.1 hypothetical protein -
  ACMHDP_RS07360 (ACMHDP_07360) - 1439639..1440019 (+) 381 WP_414842282.1 PH domain-containing protein -

Sequence

Protein


Download         Length: 429 a.a.        Molecular weight: 44575.38 Da        Isoelectric Point: 4.2548

>NTDB_id=1094440 ACMHDP_RS07330 WP_414840690.1 1434863..1436152(+) (htrA) [Enterococcus saccharolyticus strain GXN23C125Es]
MARKNVTSNRTSTGVLKKFGIGLLGGILGGMLSVGGFYYATGANEAASANEPLTSESTKDSTSDAQVSNVKVNVNSDITS
AVEKVQNSVVSIINLQASSSQSQWLNPFETQEESSSDLQPVGEGSGVIYKKDGKDAYIVTNNHVVDGQQGLEVVLTDGTK
VKAELVGSDAYTDLAVLKIASDKVDTVATFGDSDSLKVGEPAIAIGSPLGSDYANSVTQGIISSLNRLVTNTNESGQTIS
INAIQTDAAINPGNSGGPLINVAGQVIGINSSKIASSSGSGVSVEGMGFAIPSNDVTNVIEQLETKGEVTRPALGISMVD
LSSISTQQQEQILKVPSSVVNGVVVSSVGSATPAEKAGIQQYDVITKIDGKEISSGTELRSALYSKSVGDTIDVTFYRED
KEQTVKVELSVDQSIINNQNQTQSIQPQN

Nucleotide


Download         Length: 1290 bp        

>NTDB_id=1094440 ACMHDP_RS07330 WP_414840690.1 1434863..1436152(+) (htrA) [Enterococcus saccharolyticus strain GXN23C125Es]
ATGGCTCGAAAAAATGTTACATCCAATAGAACAAGTACTGGTGTATTGAAAAAATTTGGGATTGGTTTACTTGGAGGAAT
ACTCGGTGGTATGCTAAGTGTGGGCGGTTTCTACTACGCCACTGGTGCAAACGAAGCAGCTTCTGCTAATGAACCACTTA
CTAGCGAAAGTACCAAAGATTCTACGAGCGATGCCCAAGTAAGCAACGTCAAAGTCAATGTGAATAGCGATATTACTTCC
GCTGTTGAAAAAGTCCAAAATTCAGTGGTATCTATCATTAATTTACAAGCAAGCTCTTCACAAAGTCAATGGTTAAATCC
TTTTGAAACACAAGAAGAAAGTAGTTCTGACCTACAACCAGTCGGTGAAGGTAGCGGTGTAATTTACAAAAAAGATGGGA
AAGATGCGTATATCGTAACCAATAACCACGTGGTTGACGGACAACAAGGACTAGAAGTTGTCTTAACGGATGGTACTAAG
GTGAAAGCTGAATTAGTTGGGTCTGATGCGTATACAGATTTAGCAGTCTTAAAAATCGCTTCTGATAAAGTTGATACTGT
AGCAACATTTGGTGATTCAGATTCATTAAAAGTTGGCGAACCAGCAATCGCGATTGGTTCTCCTTTAGGTTCTGATTATG
CTAACTCTGTTACACAAGGGATTATCTCTTCACTAAATCGTTTGGTAACTAATACTAACGAATCTGGACAAACCATTAGT
ATTAATGCCATCCAAACCGATGCGGCGATTAATCCAGGGAACTCCGGTGGTCCATTAATTAACGTTGCTGGACAAGTTAT
CGGTATTAACTCAAGTAAAATTGCTAGCTCTTCTGGTTCCGGTGTCAGTGTTGAAGGAATGGGCTTTGCGATTCCAAGTA
ATGATGTAACAAATGTCATTGAACAACTAGAAACAAAAGGTGAAGTCACTCGCCCAGCTTTAGGTATTTCAATGGTTGAT
TTGAGTAGTATTTCAACGCAACAACAAGAACAAATTCTAAAAGTACCATCTTCTGTCGTCAACGGTGTCGTCGTTTCTTC
TGTTGGTAGTGCTACTCCTGCAGAAAAAGCTGGTATCCAACAATATGACGTGATTACCAAAATTGATGGAAAAGAAATTA
GTAGCGGCACTGAATTACGCTCTGCCCTATATAGCAAATCTGTGGGTGATACTATTGACGTAACGTTCTATCGTGAAGAC
AAAGAACAAACAGTCAAAGTTGAGTTATCTGTTGACCAATCTATCATCAATAACCAAAATCAAACACAAAGTATTCAACC
ACAAAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(124-269)

PDZ domain (PDZ_2)

(312-409)

Peptidase family M50 (Peptidase_M50)

(262-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.949

92.075

0.515
  htrA Streptococcus mitis NCTC 12261

54.96

86.946

0.478
  htrA Streptococcus gordonii str. Challis substr. CH1

52.308

90.909

0.476
  htrA Streptococcus pneumoniae TIGR4

58.735

77.389

0.455
  htrA Streptococcus pneumoniae D39

58.735

77.389

0.455
  htrA Streptococcus pneumoniae Rx1

58.735

77.389

0.455
  htrA Streptococcus pneumoniae R6

58.735

77.389

0.455

Multiple sequence alignment