Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   ACJWMD_RS05385 Genome accession   NZ_CP177182
Coordinates   1167354..1168061 (-) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain MRD6060     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1162354..1173061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS05360 - 1163021..1164235 (+) 1215 WP_004182608.1 aminoacyltransferase -
  ACJWMD_RS05365 - 1164337..1164613 (-) 277 Protein_1006 ISL3 family transposase -
  ACJWMD_RS05370 - 1164785..1165144 (-) 360 WP_004182609.1 YbaN family protein -
  ACJWMD_RS05375 vicX 1165203..1166015 (-) 813 WP_004182610.1 MBL fold metallo-hydrolase Regulator
  ACJWMD_RS05380 vicK 1166021..1167361 (-) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACJWMD_RS05385 vicR 1167354..1168061 (-) 708 WP_002884978.1 response regulator YycF Regulator
  ACJWMD_RS05390 - 1168346..1169113 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  ACJWMD_RS05395 - 1169123..1169956 (+) 834 WP_004182611.1 transporter substrate-binding domain-containing protein -
  ACJWMD_RS05400 - 1169974..1170672 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  ACJWMD_RS05405 - 1170684..1171334 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  ACJWMD_RS05410 - 1171525..1172292 (+) 768 WP_002884172.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=1086015 ACJWMD_RS05385 WP_002884978.1 1167354..1168061(-) (vicR) [Streptococcus salivarius strain MRD6060]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1086015 ACJWMD_RS05385 WP_002884978.1 1167354..1168061(-) (vicR) [Streptococcus salivarius strain MRD6060]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCGATTTCGGATATCATCAAGTTTAATCTAACTAAAGAAGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment