Detailed information NTG1085972

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: ACJWMC_RS09660
• Genome accession: NZ_CP177181
• Coordinates: 2053445..2054545 (-)
• Length: 366 a.a.
• NCBI ID: WP_155115607.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain MRD1919
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2048445..2059545

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJWMC_RS09620	-	2049058..2049255 (-)	198	WP_037598528.1	helix-turn-helix transcriptional regulator	-
ACJWMC_RS09625	-	2049502..2050695 (-)	1194	WP_002892033.1	acetate kinase	-
ACJWMC_RS09630	comYH	2050752..2051708 (-)	957	WP_002885753.1	class I SAM-dependent methyltransferase	Machinery gene
ACJWMC_RS09635	comGG	2051753..2052070 (-)	318	WP_021144683.1	competence type IV pilus minor pilin ComGG	-
ACJWMC_RS09640	comYF	2052048..2052485 (-)	438	WP_002887014.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACJWMC_RS09645	comGE	2052472..2052702 (-)	231	WP_014635119.1	competence type IV pilus minor pilin ComGE	-
ACJWMC_RS09650	comYD	2052734..2053162 (-)	429	WP_260312930.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACJWMC_RS09655	comYC	2053122..2053436 (-)	315	WP_037611125.1	competence type IV pilus major pilin ComGC	Machinery gene
ACJWMC_RS09660	comYB	2053445..2054545 (-)	1101	WP_155115607.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACJWMC_RS09665	comYA	2054427..2055368 (-)	942	WP_002885658.1	competence type IV pilus ATPase ComGA	Machinery gene
ACJWMC_RS09670	-	2055448..2055810 (-)	363	WP_002885749.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41634.62 Da
• Isoelectric Point: 10.0357

>NTDB_id=1085972 ACJWMC_RS09660 WP_155115607.1 2053445..2054545(-) (comYB) [Streptococcus salivarius strain MRD1919]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGADLEEGLMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=1085972 ACJWMC_RS09660 WP_155115607.1 2053445..2054545(-) (comYB) [Streptococcus salivarius strain MRD1919]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCGCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCTCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AACCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCCAAGCTATTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGGCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.81	93.716	0.514
comYB	Streptococcus mutans UA159	54.81	93.716	0.514
comYB	Streptococcus gordonii str. Challis substr. CH1	51.02	93.716	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	49.568	94.809	0.47
comGB/cglB	Streptococcus mitis SK321	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae Rx1	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae D39	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae R6	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae TIGR4	49.112	92.35	0.454
comGB	Lactococcus lactis subsp. cremoris KW2	45.946	90.984	0.418