Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   ACJWMC_RS01500 Genome accession   NZ_CP177181
Coordinates   283465..284364 (+) Length   299 a.a.
NCBI ID   WP_002889920.1    Uniprot ID   J7T612
Organism   Streptococcus salivarius strain MRD1919     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 278465..289364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS01480 trkA 279629..280978 (-) 1350 WP_002889909.1 Trk system potassium transporter TrkA -
  ACJWMC_RS01485 - 281256..281765 (+) 510 WP_021143543.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  ACJWMC_RS01490 - 282076..282633 (+) 558 WP_037597409.1 ECF transporter S component -
  ACJWMC_RS01495 - 282636..283286 (+) 651 WP_002889918.1 phosphatase PAP2 family protein -
  ACJWMC_RS01500 comR 283465..284364 (+) 900 WP_002889920.1 helix-turn-helix transcriptional regulator Regulator
  ACJWMC_RS01505 comA 284539..286635 (+) 2097 WP_002889921.1 peptide cleavage/export ABC transporter Regulator
  ACJWMC_RS01510 - 286746..287078 (+) 333 WP_002886546.1 DUF805 domain-containing protein -
  ACJWMC_RS01515 - 287129..288247 (-) 1119 WP_050989604.1 DUF4153 domain-containing protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35208.67 Da        Isoelectric Point: 5.5562

>NTDB_id=1085922 ACJWMC_RS01500 WP_002889920.1 283465..284364(+) (comR) [Streptococcus salivarius strain MRD1919]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDKLSYIAKRLGKHMTDLLDHDNITIPDEYYE
MKNRLIKFPTYRNPERIKAKLALIEEVYEKFFELLPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QFYSYKPSVFVLKAKYELLHKGNKKEAAENYDKAIMFASVLEDSVLEESIKAGKAADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=1085922 ACJWMC_RS01500 WP_002889920.1 283465..284364(+) (comR) [Streptococcus salivarius strain MRD1919]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAGCAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGTCAGTTAATTCGCATTGAAAAAGGGGAGTCGCTCCCGTCTTTGGATAAATTATCTT
ATATTGCAAAACGTCTAGGAAAACATATGACCGATTTATTGGATCATGATAATATTACTATCCCTGACGAATACTACGAG
ATGAAGAATCGTCTGATTAAGTTTCCAACGTATAGAAATCCAGAAAGAATAAAGGCTAAACTTGCCTTAATTGAGGAGGT
CTATGAGAAATTCTTTGAACTTCTTCCAGAAGAAGAATTGTTAACTCTAGATATTTTGGAAAATATTTTGAGTTTTACTA
GTTGGGAAGAGAGTCCTAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTTATTGACTACTATTTCTTCCATCTTTATGGAAGAAAACAGTATGATAAAAAACTTTTTGAAAGAAT
CGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTCTATAATATTGTTTTGTTTAATGATTTGATGGCTATCG
CTGCTTTGAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTTATAGAAAAATCA
CAATTCTATAGCTATAAACCTAGTGTTTTTGTTCTCAAAGCCAAATATGAACTTCTTCATAAAGGAAACAAGAAAGAGGC
TGCAGAAAATTACGATAAGGCCATAATGTTTGCTTCCGTTTTAGAAGACTCGGTACTAGAAGAAAGTATAAAGGCAGGTA
AAGCGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7T612

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius strain HSISS4

99.331

100

0.993
  comR Streptococcus salivarius SK126

98.328

100

0.983
  comR Streptococcus thermophilus LMG 18311

95.652

100

0.957
  comR Streptococcus thermophilus LMD-9

94.983

100

0.95
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.475

100

0.425
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421

Multiple sequence alignment