Detailed information NTG1085833

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: ACJVC4_RS09640
• Genome accession: NZ_CP177179
• Coordinates: 2055265..2056365 (-)
• Length: 366 a.a.
• NCBI ID: WP_155115607.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain MRD-NRLLH
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2050265..2061365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJVC4_RS09600	-	2050878..2051075 (-)	198	WP_037598528.1	helix-turn-helix transcriptional regulator	-
ACJVC4_RS09605	-	2051322..2052515 (-)	1194	WP_002892033.1	acetate kinase	-
ACJVC4_RS09610	comYH	2052572..2053528 (-)	957	WP_002885753.1	class I SAM-dependent methyltransferase	Machinery gene
ACJVC4_RS09615	comGG	2053573..2053890 (-)	318	WP_021144683.1	competence type IV pilus minor pilin ComGG	-
ACJVC4_RS09620	comYF	2053868..2054305 (-)	438	WP_002887014.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACJVC4_RS09625	comGE	2054292..2054522 (-)	231	WP_014635119.1	competence type IV pilus minor pilin ComGE	-
ACJVC4_RS09630	comYD	2054554..2054982 (-)	429	WP_260312930.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACJVC4_RS09635	comYC	2054942..2055256 (-)	315	WP_037611125.1	competence type IV pilus major pilin ComGC	Machinery gene
ACJVC4_RS09640	comYB	2055265..2056365 (-)	1101	WP_155115607.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACJVC4_RS09645	comYA	2056247..2057188 (-)	942	WP_002885658.1	competence type IV pilus ATPase ComGA	Machinery gene
ACJVC4_RS09650	-	2057268..2057630 (-)	363	WP_002885749.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41634.62 Da
• Isoelectric Point: 10.0357

>NTDB_id=1085833 ACJVC4_RS09640 WP_155115607.1 2055265..2056365(-) (comYB) [Streptococcus salivarius strain MRD-NRLLH]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGADLEEGLMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=1085833 ACJVC4_RS09640 WP_155115607.1 2055265..2056365(-) (comYB) [Streptococcus salivarius strain MRD-NRLLH]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCGCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCTCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AACCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCCAAGCTATTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGGCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.81	93.716	0.514
comYB	Streptococcus mutans UA159	54.81	93.716	0.514
comYB	Streptococcus gordonii str. Challis substr. CH1	51.02	93.716	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	49.568	94.809	0.47
comGB/cglB	Streptococcus mitis SK321	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae Rx1	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae D39	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae R6	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae TIGR4	49.112	92.35	0.454
comGB	Lactococcus lactis subsp. cremoris KW2	45.946	90.984	0.418