Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ACK2I7_RS01985 Genome accession   NZ_CP176632
Coordinates   397428..399578 (+) Length   716 a.a.
NCBI ID   WP_003025436.1    Uniprot ID   A0AAP6BMV2
Organism   Streptococcus anginosus strain SFAD 40     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 392428..404578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS01960 frr 392958..393515 (+) 558 WP_003034284.1 ribosome recycling factor -
  ACK2I7_RS01965 cvfB 393862..394716 (+) 855 WP_003025448.1 RNA-binding virulence regulatory protein CvfB -
  ACK2I7_RS01970 holA 394797..395834 (+) 1038 WP_021001445.1 DNA polymerase III subunit delta -
  ACK2I7_RS01975 - 395905..396510 (+) 606 WP_021001446.1 superoxide dismutase -
  ACK2I7_RS01980 - 396573..396947 (-) 375 WP_037590248.1 hypothetical protein -
  ACK2I7_RS01985 comA/nlmT 397428..399578 (+) 2151 WP_003025436.1 peptide cleavage/export ABC transporter Regulator
  ACK2I7_RS01990 - 399589..400950 (+) 1362 WP_021001448.1 bacteriocin secretion accessory protein -
  ACK2I7_RS01995 - 401043..401192 (+) 150 WP_003025431.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ACK2I7_RS02000 - 401237..402544 (-) 1308 WP_021001449.1 sensor histidine kinase -
  ACK2I7_RS02005 comE/blpR 402549..403295 (-) 747 WP_037590320.1 response regulator transcription factor Regulator
  ACK2I7_RS02010 - 403464..404177 (-) 714 WP_021001450.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80424.99 Da        Isoelectric Point: 9.4752

>NTDB_id=1081701 ACK2I7_RS01985 WP_003025436.1 397428..399578(+) (comA/nlmT) [Streptococcus anginosus strain SFAD 40]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKAKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLTSFLPLI
FKQRSLIFYIVLASLLVTLINIVSSYYLQGILDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIILSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLFILIMVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEETRYQKIDSEFVNYLDKSFTLSKYSIMQTSLKQGAQFI
LNVVILWVGASLAMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQVITEKNFLA
GDITFHDVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILANLTLGTNQIFSQEEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHTKLMERKGFYHHLFSK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=1081701 ACK2I7_RS01985 WP_003025436.1 397428..399578(+) (comA/nlmT) [Streptococcus anginosus strain SFAD 40]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGCTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACTAAGATATCAAAAGAGACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAGAATGGGCTTACTAGCTTTTTACCACTCATC
TTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTTGTGACCCTCATTAACATTGTTAGTTCTTATTA
TCTGCAAGGGATTTTGGATGAATACATTCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTATACTTAGTCAGCGATTAACCATCGATGTA
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAAATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTTTATTTTGATAA
TGGTAGGAGGGGTACTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACAGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTTATGCAAAGTAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACGATTAAATCTTTAACCAGCGAAGAAACTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCCATTATGCAGACATCTCTCAAACAAGGAGCACAATTTATT
TTGAATGTTGTTATTCTATGGGTTGGAGCATCTCTGGCTATGTCTCAAAAAATTTCGATTGGACAGCTGATTACTTTTAA
TGCACTCCTTTCGTATTTTACAAGTCCACTTGAAAGTATCATCAATCTGCAAACTAAGCTGCAGTCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATCTGGTAGAATCCGAATTCAAAACCAAACAAGTCATTACAGAGAAAAATTTCTTGGCT
GGTGACATTACTTTTCATGATGTTTCTTATAAATATGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTTAATGGAAATGATCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCCATCTTAGCAAATCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGATGAGGCAACGAGCGGATTGGATGTTTTAACTGAGAAAAAGGTCATTGACAATCTGATGGGCTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAAGTGATTGTTCTTGATAAAGGACAGA
TTATTGAAACTGGTTCCCACACTAAATTGATGGAAAGAAAAGGTTTTTATCATCATTTATTTAGCAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(167-437)

ABC transporter (ABC_tran)

(499-648)

Peptidase C39 family (Peptidase_C39)

(6-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.227

99.022

0.705
  comA Streptococcus mitis NCTC 12261

66.245

99.302

0.658
  comA Streptococcus mitis SK321

65.963

99.302

0.655
  comA Streptococcus gordonii str. Challis substr. CH1

65.541

99.302

0.651
  comA Streptococcus pneumoniae D39

65.401

99.302

0.649
  comA Streptococcus pneumoniae R6

65.401

99.302

0.649
  comA Streptococcus pneumoniae Rx1

65.401

99.302

0.649
  comA Streptococcus pneumoniae TIGR4

64.979

99.302

0.645

Multiple sequence alignment