Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACK2I7_RS02005 Genome accession   NZ_CP176632
Coordinates   402549..403295 (-) Length   248 a.a.
NCBI ID   WP_037590320.1    Uniprot ID   A0AAP6EN96
Organism   Streptococcus anginosus strain SFAD 40     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 397549..408295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS01990 - 399589..400950 (+) 1362 WP_021001448.1 bacteriocin secretion accessory protein -
  ACK2I7_RS01995 - 401043..401192 (+) 150 WP_003025431.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ACK2I7_RS02000 - 401237..402544 (-) 1308 WP_021001449.1 sensor histidine kinase -
  ACK2I7_RS02005 comE/blpR 402549..403295 (-) 747 WP_037590320.1 response regulator transcription factor Regulator
  ACK2I7_RS02010 - 403464..404177 (-) 714 WP_021001450.1 CPBP family intramembrane glutamic endopeptidase -
  ACK2I7_RS02015 - 404409..404633 (+) 225 WP_003025424.1 Blp family class II bacteriocin -
  ACK2I7_RS02020 - 404721..405041 (+) 321 WP_003037422.1 hypothetical protein -
  ACK2I7_RS02025 - 405049..405282 (+) 234 WP_003025420.1 garvicin Q family class II bacteriocin -
  ACK2I7_RS02030 - 405334..405624 (+) 291 WP_021001453.1 bacteriocin immunity protein -
  ACK2I7_RS02035 - 405776..406096 (+) 321 WP_057489587.1 hypothetical protein -
  ACK2I7_RS02040 - 406326..406556 (+) 231 WP_021001454.1 Blp family class II bacteriocin -
  ACK2I7_RS02045 - 407009..408058 (+) 1050 WP_021001455.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 28788.23 Da        Isoelectric Point: 8.4655

>NTDB_id=1081702 ACK2I7_RS02005 WP_037590320.1 402549..403295(-) (comE/blpR) [Streptococcus anginosus strain SFAD 40]
MNIFILEDDLTQQYYMETIVEKIIEKHRLQYHHFEVFGKPKQLLEAISEKGSHQVFFLDIEIKTEEKKGLDVAKKIREID
PYAIIVFVTSHSELMPAAFKLQVGALDYLDKSLSKETFKKRIETALLHTENLTGKGLADDSLLFETPHTQIQVPFKDILY
IETSSRPHRLVLYTHRGRTEFTANLSDMLKKEKRFYQCHRSFVVNPANVHQVDKVNHILHFQNGATCLVSRSKIKGLTEA
IAALHRRE

Nucleotide


Download         Length: 747 bp        

>NTDB_id=1081702 ACK2I7_RS02005 WP_037590320.1 402549..403295(-) (comE/blpR) [Streptococcus anginosus strain SFAD 40]
ATGAATATTTTTATTTTAGAAGATGATCTTACTCAACAATATTATATGGAGACTATTGTTGAAAAAATTATCGAAAAACA
TCGTCTTCAATATCACCATTTTGAAGTTTTTGGAAAACCTAAACAATTACTAGAAGCCATATCTGAGAAAGGAAGCCATC
AGGTTTTCTTTTTGGATATTGAAATCAAAACTGAAGAAAAAAAGGGCTTAGACGTCGCCAAAAAGATACGCGAGATAGAT
CCTTATGCCATTATTGTCTTTGTAACCAGTCACTCTGAATTGATGCCGGCAGCGTTTAAACTGCAAGTCGGCGCCCTTGA
CTATCTTGACAAATCGTTATCAAAAGAAACTTTTAAAAAACGGATCGAAACTGCGCTGCTACATACTGAAAACCTAACAG
GCAAAGGCCTGGCAGACGATTCTCTTCTCTTTGAAACACCTCATACACAAATACAAGTGCCGTTTAAAGATATTCTTTAC
ATCGAAACTTCCTCTCGCCCTCACCGTTTAGTACTTTACACACATAGAGGGCGTACGGAATTTACTGCCAATCTTTCAGA
TATGTTAAAAAAAGAAAAACGGTTCTACCAATGTCATCGTTCCTTTGTTGTTAACCCAGCTAATGTCCATCAAGTGGATA
AAGTAAATCATATCCTTCACTTCCAGAATGGTGCTACTTGTCTTGTTTCTAGATCAAAAATAAAAGGGCTAACAGAAGCT
ATTGCAGCCCTGCACCGGAGGGAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

50.202

99.597

0.5
  comE/comE1 Streptococcus equinus JB1

45.992

95.565

0.44

Multiple sequence alignment