Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ACK2I7_RS01270 Genome accession   NZ_CP176632
Coordinates   258349..260223 (+) Length   624 a.a.
NCBI ID   WP_021001359.1    Uniprot ID   A0AAP6BPS5
Organism   Streptococcus anginosus strain SFAD 40     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 253349..265223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS01255 fmt 255355..256290 (+) 936 WP_021001357.1 methionyl-tRNA formyltransferase -
  ACK2I7_RS01260 rsmB 256280..257593 (+) 1314 WP_021001358.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACK2I7_RS01265 - 257612..258352 (+) 741 WP_003025814.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACK2I7_RS01270 stkP 258349..260223 (+) 1875 WP_021001359.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACK2I7_RS01275 liaF 260484..261182 (+) 699 WP_003025810.1 cell wall-active antibiotics response protein LiaF -
  ACK2I7_RS01280 - 261179..262174 (+) 996 WP_021001360.1 sensor histidine kinase -
  ACK2I7_RS01285 - 262176..262808 (+) 633 WP_021001361.1 response regulator transcription factor -
  ACK2I7_RS01290 - 262848..264248 (+) 1401 WP_057489579.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACK2I7_RS01295 - 264250..264624 (+) 375 WP_021001363.1 S1 RNA-binding domain-containing protein -
  ACK2I7_RS01300 - 264750..265067 (-) 318 WP_041784094.1 DUF960 domain-containing protein -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67719.81 Da        Isoelectric Point: 9.4135

>NTDB_id=1081694 ACK2I7_RS01270 WP_021001359.1 258349..260223(+) (stkP) [Streptococcus anginosus strain SFAD 40]
MIQVGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKSTPTPTKEAVS
SKPTPKPKAKKKRRLRTRYKVLLSAVVLVIVALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVK
KDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKSQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVDQTP
AAGSTYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQAPEAGQS
LNLKSDRIILYVYEPKTEDSSTSESSSQSDSSSDKTSPSSSSSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=1081694 ACK2I7_RS01270 WP_021001359.1 258349..260223(+) (stkP) [Streptococcus anginosus strain SFAD 40]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAAAATCATCAAACAAATTGGTCGAGGTGGCATGGCAGATGTCTA
CTTGGCGAAAGACTTGATTTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAATTACCAGACGGATCCAATTG
CTGTAGCACGTTTTCAAAGAGAAGCACGCGCCATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGTCAGCAGTATCTAGCAATGGAATATGTGGCTGGACTCGACTTAAAGCGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTTCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCACACACGCACGGGATTGTTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTCACTGACTTTGGAATTGCGGTAGCT
TTTGCAGAAACGAGCTTAACGCAAACCAACTCTATGCTGGGATCTGTGCATTATCTATCACCAGAACAGGCACGTGGTTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACATATCCCTTATGACG
GAGATAGTGCTGTTACAATTGCTTTACAGCATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAATGTTCCA
CAAGCATTAGAAAATGTAGTCATCAAGGCAACGGCTAAAAAATTGACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
GGATTTATCAAGCTGTTTATCTGCTGACCGTCGAAATGAGAAAAAACTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACACTGCCGAAAGTATCACAAAATACCTTGACTTCTGCGACGAAGTCAACACCTACTCCTACAAAAGAAGCAGTCAGT
AGTAAGCCTACGCCTAAGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGCTATAAAGTTTTGTTATCAGCGGTGGT
TTTAGTCATCGTAGCTCTGGTGGCTTTAGTCTATTTGAGTCCGTCAAATGTAAAAATTCCAGATGTTACTGGAAAAACTA
TTGCCCAAGCTCGTTCTGCAATTGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAA
AAAGACTCAGTCATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAA
AGGGACTAAAACTTTTATTATGGAAGATTATAAAAGTCAGAAAAGAGCAGATGCCATCAACAATCTGGTACAAAAATACA
AGGTTTCAAAAGGCTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCA
GCAGCAGGCAGCACTTATGATTTGACTTCAAAGACACGTATCACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGAT
GCCAAGCTATATCGGTTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTG
AAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAGCCCCAGAAGCTGGTCAGTCT
TTGAATTTGAAGAGTGATCGCATTATCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGAAAGTAGTTC
ACAATCTGATAGCAGCTCAGATAAAACTAGCCCATCCTCTAGCAGTTCGTCAACTAGTGGTAATGATGGAAGCAGCTCAA
AAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(364-427)

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(433-500)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

65.812

93.75

0.617
  stkP Streptococcus pneumoniae D39

65.47

93.75

0.614
  stkP Streptococcus pneumoniae R6

65.47

93.75

0.614
  stkP Streptococcus pneumoniae Rx1

65.299

93.75

0.612
  pknB Streptococcus mutans UA159

58.974

93.75

0.553
  stkP/pknB Streptococcus salivarius strain HSISS4

55.333

96.154

0.532

Multiple sequence alignment