Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   ACKWPP_RS08350 Genome accession   NZ_CP176418
Coordinates   1643583..1644287 (-) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain KKAHC02     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1638583..1649287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWPP_RS08335 (ACKWPP_08335) vga(F) 1639791..1641176 (-) 1386 WP_409373797.1 ABC-F type ribosomal protection protein Vga(F) -
  ACKWPP_RS08340 (ACKWPP_08340) vicX 1641431..1642234 (-) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  ACKWPP_RS08345 (ACKWPP_08345) micB 1642241..1643590 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACKWPP_RS08350 (ACKWPP_08350) micA 1643583..1644287 (-) 705 WP_002935840.1 response regulator YycF Regulator
  ACKWPP_RS08355 (ACKWPP_08355) - 1644481..1645242 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  ACKWPP_RS08360 (ACKWPP_08360) - 1645253..1646092 (+) 840 WP_409373798.1 transporter substrate-binding domain-containing protein -
  ACKWPP_RS08365 (ACKWPP_08365) - 1646107..1646805 (+) 699 WP_409373799.1 amino acid ABC transporter permease -
  ACKWPP_RS08370 (ACKWPP_08370) - 1646820..1647479 (+) 660 WP_014637676.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=1080073 ACKWPP_RS08350 WP_002935840.1 1643583..1644287(-) (micA) [Streptococcus suis strain KKAHC02]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1080073 ACKWPP_RS08350 WP_002935840.1 1643583..1644287(-) (micA) [Streptococcus suis strain KKAHC02]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGTTGGAGCTCACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACAATCCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATATATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment