Detailed information NTG1079992

Bioinformatically predicted

Overview

• Name: comFC
• Type: Machinery gene
• Locus tag: ACKWCM_RS16710
• Genome accession: NZ_CP176416
• Coordinates: 3258986..3259642 (-)
• Length: 218 a.a.
• NCBI ID: WP_244948474.1
• Uniprot ID: A0A5C0WI32
• Organism: Bacillus safensis strain GUCCb3-7
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3253986..3264642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKWCM_RS16675 (ACKWCM_16675)	fliW	3254124..3254558 (-)	435	WP_024423615.1	flagellar assembly protein FliW	-
ACKWCM_RS16680 (ACKWCM_16680)	-	3254587..3255165 (-)	579	WP_024426253.1	DUF6470 family protein	-
ACKWCM_RS16685 (ACKWCM_16685)	flgL	3255212..3256120 (-)	909	WP_024423617.1	flagellar hook-associated protein FlgL	-
ACKWCM_RS16690 (ACKWCM_16690)	flgK	3256130..3257650 (-)	1521	WP_149126230.1	flagellar hook-associated protein FlgK	-
ACKWCM_RS16695 (ACKWCM_16695)	-	3257666..3258148 (-)	483	WP_149126229.1	flagellar protein FlgN	-
ACKWCM_RS16700 (ACKWCM_16700)	flgM	3258167..3258430 (-)	264	WP_024423620.1	flagellar biosynthesis anti-sigma factor FlgM	-
ACKWCM_RS16705 (ACKWCM_16705)	-	3258510..3258929 (-)	420	WP_024423621.1	TIGR03826 family flagellar region protein	-
ACKWCM_RS16710 (ACKWCM_16710)	comFC	3258986..3259642 (-)	657	WP_244948474.1	ComF family protein	Machinery gene
ACKWCM_RS16715 (ACKWCM_16715)	-	3259669..3259962 (-)	294	WP_025093967.1	late competence development ComFB family protein	-
ACKWCM_RS16720 (ACKWCM_16720)	comFA	3260011..3261411 (-)	1401	WP_409362645.1	DEAD/DEAH box helicase	Machinery gene
ACKWCM_RS16725 (ACKWCM_16725)	-	3261529..3262371 (-)	843	WP_024423625.1	DegV family protein	-
ACKWCM_RS16730 (ACKWCM_16730)	degU	3262587..3263276 (-)	690	WP_008348273.1	two-component system response regulator DegU	Regulator
ACKWCM_RS16735 (ACKWCM_16735)	degS	3263341..3264516 (-)	1176	WP_003213166.1	sensor histidine kinase	Regulator

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 24946.05 Da
• Isoelectric Point: 9.7972

>NTDB_id=1079992 ACKWCM_RS16710 WP_244948474.1 3258986..3259642(-) (comFC) [Bacillus safensis strain GUCCb3-7]
MPAFTWKSFLLLNDDHLCVACKNHLVKIERPICPTCGRAQSNDQLCQDCNRWNERSDSIKILVKNRSVYTYNELMKDVLA
RFKFRGDTALAELFQKDVQAAFKHSFCIKDPLLIPIPLSHERLKERGFNQSVLIASLLDKPILQPLVKIHQSKQSKKKKN
ERLDQKGLFQIKQTDAIVQRDIILVDDIYTTGATIYDAARILKDAGAKSVSSFTLIRS

Nucleotide

• Length: 657 bp

>NTDB_id=1079992 ACKWCM_RS16710 WP_244948474.1 3258986..3259642(-) (comFC) [Bacillus safensis strain GUCCb3-7]
GTGCCTGCTTTTACATGGAAATCATTCCTACTATTAAATGATGATCACCTTTGTGTAGCATGTAAGAATCACTTAGTAAA
GATTGAGCGTCCTATTTGTCCAACATGCGGAAGGGCGCAGTCAAATGACCAATTGTGCCAGGACTGTAACAGATGGAATG
AACGCTCTGATTCTATTAAAATCCTTGTAAAAAATAGGTCAGTTTATACTTACAACGAGTTGATGAAAGATGTCCTTGCC
CGCTTTAAATTTCGGGGTGATACGGCTTTAGCTGAGCTGTTTCAAAAAGATGTACAAGCAGCATTTAAACATTCCTTCTG
CATAAAAGACCCATTGCTGATACCGATTCCTTTAAGTCATGAAAGACTAAAAGAAAGAGGATTTAATCAGTCCGTGTTAA
TCGCTTCTTTGCTAGATAAGCCAATATTGCAGCCACTCGTGAAAATACATCAAAGTAAGCAGTCTAAAAAAAAGAAAAAT
GAACGCCTAGATCAAAAAGGATTGTTTCAAATAAAGCAAACAGATGCGATTGTTCAAAGGGATATTATATTAGTTGATGA
TATCTATACAACGGGAGCAACCATCTATGATGCGGCAAGAATTTTGAAAGACGCAGGTGCTAAAAGTGTTTCTTCTTTTA
CGTTGATACGTAGTTAA

Domains

Predicted by InterproScan.

• Double zinc ribbon domain (DZR_2) (14-49)

• Phosphoribosyl transferase domain (Pribosyltran) (132-216)

3D structure

• AlphaFold DB: A0A5C0WI32

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFC	Bacillus subtilis subsp. subtilis str. 168	50	99.083	0.495
comFC/cflB	Streptococcus pneumoniae Rx1	36.744	98.624	0.362
comFC/cflB	Streptococcus pneumoniae D39	36.744	98.624	0.362
comFC/cflB	Streptococcus pneumoniae R6	36.744	98.624	0.362
comFC/cflB	Streptococcus pneumoniae TIGR4	36.744	98.624	0.362