Detailed information NTG0107365

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ACAM22_RS09640
• Genome accession: NZ_AP028929
• Coordinates: 2062679..2064832 (-)
• Length: 717 a.a.
• NCBI ID: WP_261053278.1
• Uniprot ID: -
• Organism: Streptococcus sp. SN-1
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2057679..2069832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM22_RS09630 (MASAN616_18520)	purC	2060439..2061146 (-)	708	WP_265471988.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
ACAM22_RS09635 (MASAN616_18530)	comB	2061317..2062666 (-)	1350	WP_369606757.1	competence pheromone export protein ComB	Regulator
ACAM22_RS09640 (MASAN616_18540)	comA	2062679..2064832 (-)	2154	WP_261053278.1	peptide cleavage/export ABC transporter ComA	Regulator
ACAM22_RS09645 (MASAN616_18550)	-	2065455..2065685 (-)	231	WP_261053279.1	bacteriocin immunity protein	-
ACAM22_RS09650 (MASAN616_18560)	-	2065764..2065943 (-)	180	WP_261053280.1	hypothetical protein	-
ACAM22_RS09655 (MASAN616_18570)	-	2066025..2066240 (-)	216	WP_261053283.1	bacteriocin immunity protein	-
ACAM22_RS09660 (MASAN616_18580)	-	2066244..2066411 (-)	168	WP_001047583.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACAM22_RS09665 (MASAN616_18590)	-	2066420..2066620 (-)	201	WP_261053285.1	hypothetical protein	-
ACAM22_RS09670 (MASAN616_18600)	-	2066769..2066969 (-)	201	WP_049512841.1	SPPN_00645 family bacteriocin-like peptide	-
ACAM22_RS09675 (MASAN616_18610)	-	2067002..2067190 (-)	189	WP_084890454.1	hypothetical protein	-
ACAM22_RS09680 (MASAN616_18620)	-	2067210..2067392 (-)	183	WP_050967307.1	hypothetical protein	-
ACAM22_RS09685 (MASAN616_18630)	-	2067503..2067643 (-)	141	WP_155640144.1	hypothetical protein	-
ACAM22_RS09690 (MASAN616_18640)	-	2067655..2067783 (-)	129	WP_000658221.1	smi_0059.1 family bacteriocin-like peptide	-
ACAM22_RS09695 (MASAN616_18650)	-	2068392..2068628 (-)	237	WP_000136444.1	acyl carrier protein	-
ACAM22_RS09700 (MASAN616_18660)	plsX	2068634..2069626 (-)	993	WP_261053297.1	phosphate acyltransferase PlsX	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80275.32 Da
• Isoelectric Point: 6.5178

>NTDB_id=107365 ACAM22_RS09640 WP_261053278.1 2062679..2064832(-) (comA) [Streptococcus sp. SN-1]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQEKDSIYIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGDMTFKNVHYKYGYGRDVLSDINLTIPQGSKVAFVGISGSGKTTLAKMMVNFYNPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=107365 ACAM22_RS09640 WP_261053278.1 2062679..2064832(-) (comA) [Streptococcus sp. SN-1]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAGGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGTTATTATTCTTTGGCTCACTTGCGAGAATTGGCTAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATTGGTTTTGAGACGCGGGCCATCAAGGCGGATATGACGCTTTTTGACTTGCCAGATCTG
ACTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGAAAATTGCTCCACTACTATGTGGTGACTGGGCAGGAGAAGGACAG
CATTTATATTGCAGATCCAGATCCTGGGGTGAAATTGACCAAACTGCCACGTGAGCGTTTTGCGGAAGAATGGACAGGAG
TGACTCTGTTTATGGCCCCTAGTCCAGACTACAAGCCTCATAAGGATCAAAAGAATGGTTTGCTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAATATCGTTTTGGCGACGCTCTTGGTAACCGTGATTAATATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGCTTGGGATTATTTCTATTGGGCTGGTTA
TCGTCTATATTCTCCAGCAGATCTTGTCTTATGCTCAAGAGTATCTCTTGCTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTGATTTTGTCCTATATCAAGCATGTTTTTCACCTGCCTATGTCCTTTTTTGCGACACGTCGGACAGGGGAAATCGTGTC
TCGTTTTACAGATGCTAACAGTATTATCGATGCGCTGGCTTCGACCATCCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCTCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCACTTCCTATCTATACAGTG
ATTATCTTTGCTTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAACGGTATTGAGACTATTAAGTCTTTGACCAGTGAAAGTCAACGTTACCAAAAGATTGACAAGGAAT
TTGTGGATTATCTGAAAAAATCCTTTACCTATAGTCGGGCAGAGAGTCAGCAAAAGGCTCTGAAAAAAGTTGCCCATCTC
TTGCTCAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTTATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGTTGGTTTACTTTACCAATCCTTTGGAGAATATCATCAATCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAGGTTTATCTGGTAGCTTCTGAGTTTGAGGAGAAGAAAACAGTTGAGGATCTGAGCTTGATG
AAGGGAGATATGACCTTCAAGAATGTTCACTATAAGTATGGTTATGGTAGAGACGTCTTGTCGGATATCAATTTGACCAT
TCCTCAAGGGTCTAAGGTGGCTTTTGTGGGGATTTCGGGGTCAGGTAAGACGACCTTGGCCAAGATGATGGTTAATTTTT
ACAATCCAAGTCAAGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAGGCTTTGCGCCAGTATATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCTAAGGAGGGGACGAC
ACAGGAGGATATCTTACGAGCGGTCGAGTTGGCAGAGATTCGGGAGGATATCGAGCGGATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGGGCGGGAATTTCAGGTGGGCAACGTCAGCGAATCGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCTGTCTTGATTTTGGATGAAGCGACCAGCAGTTTGGATATTTTGACAGAGAAGCGAATTGTCGATAATCTCATGGCTTT
AGATAAGACCTTGATTTTCATTGCTCACCGCTTGACCATTGCTGAGCGGACAGAGAAGGTTGTTGTCTTGGATCAGGGTA
AGATTGTTGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGGTGGTTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae Rx1	98.745	100	0.987
comA	Streptococcus pneumoniae D39	98.745	100	0.987
comA	Streptococcus pneumoniae R6	98.745	100	0.987
comA	Streptococcus mitis SK321	98.605	100	0.986
comA	Streptococcus mitis NCTC 12261	98.605	100	0.986
comA	Streptococcus pneumoniae TIGR4	98.326	100	0.983
comA	Streptococcus gordonii str. Challis substr. CH1	80.474	100	0.805
comA/nlmT	Streptococcus mutans UA159	65.272	100	0.653