Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ACAM22_RS09635 Genome accession   NZ_AP028929
Coordinates   2061317..2062666 (-) Length   449 a.a.
NCBI ID   WP_369606757.1    Uniprot ID   A0AAT9G3J2
Organism   Streptococcus sp. SN-1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2056317..2067666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS09625 (MASAN616_18510) - 2056646..2060371 (-) 3726 WP_369606756.1 phosphoribosylformylglycinamidine synthase -
  ACAM22_RS09630 (MASAN616_18520) purC 2060439..2061146 (-) 708 WP_265471988.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  ACAM22_RS09635 (MASAN616_18530) comB 2061317..2062666 (-) 1350 WP_369606757.1 competence pheromone export protein ComB Regulator
  ACAM22_RS09640 (MASAN616_18540) comA 2062679..2064832 (-) 2154 WP_261053278.1 peptide cleavage/export ABC transporter ComA Regulator
  ACAM22_RS09645 (MASAN616_18550) - 2065455..2065685 (-) 231 WP_261053279.1 bacteriocin immunity protein -
  ACAM22_RS09650 (MASAN616_18560) - 2065764..2065943 (-) 180 WP_261053280.1 hypothetical protein -
  ACAM22_RS09655 (MASAN616_18570) - 2066025..2066240 (-) 216 WP_261053283.1 bacteriocin immunity protein -
  ACAM22_RS09660 (MASAN616_18580) - 2066244..2066411 (-) 168 WP_001047583.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACAM22_RS09665 (MASAN616_18590) - 2066420..2066620 (-) 201 WP_261053285.1 hypothetical protein -
  ACAM22_RS09670 (MASAN616_18600) - 2066769..2066969 (-) 201 WP_049512841.1 SPPN_00645 family bacteriocin-like peptide -
  ACAM22_RS09675 (MASAN616_18610) - 2067002..2067190 (-) 189 WP_084890454.1 hypothetical protein -
  ACAM22_RS09680 (MASAN616_18620) - 2067210..2067392 (-) 183 WP_050967307.1 hypothetical protein -
  ACAM22_RS09685 (MASAN616_18630) - 2067503..2067643 (-) 141 WP_155640144.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49782.81 Da        Isoelectric Point: 5.7895

>NTDB_id=107364 ACAM22_RS09635 WP_369606757.1 2061317..2062666(-) (comB) [Streptococcus sp. SN-1]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATLAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGELLVQYKEGAEGVQVEAYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQVEIGNLISQTEAKIRDYQTAKSAIETGASLASQNLAYSLYQSYKSQGEENPQAKSQAVAQVEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLDQKILEVESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSTMVAEGALLAQLYPSLEKEGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAKNQIFLDSTITSIDATATKTET
GNFFKIEAETNLTSEQATKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=107364 ACAM22_RS09635 WP_369606757.1 2061317..2062666(-) (comB) [Streptococcus sp. SN-1]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTACCCAT
GTCCCTTCTGCTCGTGTTTTTGCTTGGCTTTGCAACTTTGGCAGAGAAGGAGATGAGTTTGTCTACTAGAGCTACTGTTG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGCATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTCAAGAAGGGGGAACTTCTGGTTCAATATAAGGAAGGGGCAGAAGGTGTTCAAGTAGAGGCTTATGCCAGTCAGTTGGA
CATGCTTAAGGATCAAAAAAAGCAATTGGAGTATTTGCAAAAAAGTCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAATTTGGCTACCAAGCCACCTTTCGCGACTACATCAGCCAAGCAGGTAGTCTTAGGGCTAGTACATCGCAACAAAAC
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGTCGAAATCGGCAACCTCATCAGCCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTCT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCGCAAGCTAAATCCCAGGCTGTTGCGCAGGTTGAAGCACAGCTTTCT
CAGTTAGAATCTAGTCTCGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGTTTAAG
TAGTCAATTGGAGTCTCTCAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGACCAGAAAATCTTGG
AGGTGGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTACCATGGTAGCAGAAGGTGCCCTACTAGCCCAACTCTATCCGTCCTTGGAAAAAGA
AGGGAAAGCCAAACTAACAGCCTATCTTAGTTCAAAGGATGTAGCAAGGATCAAGGTCGGTGATTCTGTTCGCTATACGA
CGACTCATGATGCCAAGAATCAAATTTTCCTAGATTCTACTATTACCAGTATTGATGCGACAGCTACTAAGACTGAAACT
GGGAATTTCTTTAAAATTGAGGCGGAGACTAATCTAACTTCTGAGCAGGCTACAAAACTTCGGTACGGGGTGGAAGGTCG
CCTACAGATGATTACGGGCAAGAAAAGTTACCTGCGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

96.882

100

0.969
  comB Streptococcus mitis NCTC 12261

95.991

100

0.96
  comB Streptococcus pneumoniae TIGR4

95.1

100

0.951
  comB Streptococcus pneumoniae D39

94.878

100

0.949
  comB Streptococcus pneumoniae Rx1

94.878

100

0.949
  comB Streptococcus pneumoniae R6

94.878

100

0.949
  comB Streptococcus gordonii str. Challis substr. CH1

56

100

0.561

Multiple sequence alignment