Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Regulator
Locus tag   ACAM22_RS00020 Genome accession   NZ_AP028929
Coordinates   1372..1497 (+) Length   41 a.a.
NCBI ID   WP_000799683.1    Uniprot ID   -
Organism   Streptococcus sp. SN-1     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1..6497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS00010 (MASAN616_00010) rlmH 611..1090 (+) 480 WP_000695936.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACAM22_RS00020 (MASAN616_00020) comC 1372..1497 (+) 126 WP_000799683.1 competence-stimulating peptide ComC Regulator
  ACAM22_RS00025 (MASAN616_00030) comD/comD2 1518..2843 (+) 1326 WP_023944979.1 competence system sensor histidine kinase ComD Regulator
  ACAM22_RS00030 (MASAN616_00040) comE 2840..3592 (+) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  ACAM22_RS00045 (MASAN616_00050) - 3842..5098 (-) 1257 WP_265471657.1 ISL3 family transposase -
  ACAM22_RS00050 (MASAN616_00060) - 5257..5799 (-) 543 WP_265471656.1 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 41 a.a.        Molecular weight: 4916.95 Da        Isoelectric Point: 10.7877

>NTDB_id=107295 ACAM22_RS00020 WP_000799683.1 1372..1497(+) (comC) [Streptococcus sp. SN-1]
MKNTVKLEQFVALKEKDLQEIKGGEMRLPKILRDFIFPRKK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=107295 ACAM22_RS00020 WP_000799683.1 1372..1497(+) (comC) [Streptococcus sp. SN-1]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCCTTGAAGGAAAAAGACTTGCAGGAGATTAAAGGTGGGGAGATGAG
ACTGCCAAAAATCCTCCGTGATTTTATTTTCCCAAGAAAAAAGTAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus mitis SK321

90.244

100

0.902
  comC/comC1 Streptococcus pneumoniae R6

85.366

100

0.854
  comC/comC1 Streptococcus pneumoniae G54

85.366

100

0.854
  comC/comC1 Streptococcus pneumoniae D39

85.366

100

0.854
  comC/comC1 Streptococcus pneumoniae Rx1

85.366

100

0.854
  comC/comC2 Streptococcus pneumoniae A66

80.488

100

0.805
  comC/comC2 Streptococcus pneumoniae TIGR4

80.488

100

0.805
  comC Streptococcus mitis NCTC 12261

74.074

65.854

0.488

Multiple sequence alignment