Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACFSN5_RS01080 Genome accession   NZ_CP172427
Coordinates   204561..205364 (+) Length   267 a.a.
NCBI ID   WP_165211838.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 199561..210364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS01065 (ACFSN5_01065) - 199740..201284 (-) 1545 WP_165211829.1 ABC transporter permease subunit -
  ACFSN5_RS01070 (ACFSN5_01070) - 201468..203396 (+) 1929 WP_165329276.1 DUF2207 domain-containing protein -
  ACFSN5_RS01075 (ACFSN5_01075) - 203550..204392 (+) 843 WP_165211835.1 undecaprenyl-diphosphate phosphatase -
  ACFSN5_RS01080 (ACFSN5_01080) mecA 204561..205364 (+) 804 WP_165211838.1 adaptor protein MecA Regulator
  ACFSN5_RS01085 (ACFSN5_01085) - 205368..206528 (+) 1161 WP_165211841.1 glycosyltransferase family 4 protein -
  ACFSN5_RS01090 (ACFSN5_01090) sufC 207133..207903 (+) 771 WP_165211844.1 Fe-S cluster assembly ATPase SufC -
  ACFSN5_RS01095 (ACFSN5_01095) sufD 208039..209301 (+) 1263 WP_165211847.1 Fe-S cluster assembly protein SufD -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30279.05 Da        Isoelectric Point: 4.0998

>NTDB_id=1067655 ACFSN5_RS01080 WP_165211838.1 204561..205364(+) (mecA) [Streptococcus sp. ZJ 1593]
MEMKQINESTLKISVSLEDLDSYGMELKDFLMPQEKTEEFFYTILDELDIPDSFKSTGMLSFRVTPRKDRVDVFVTKSEL
NESLDFEQLAEDMGDMSDMNPEDFFKNLEKNMMAQGDTEAHEKLKNLEAMLDDAIGDLPEEVQAVTTGSEDGESDARAFR
LKEEDLIPVTSYAHYVADFPNLEAVIVAAKALAVPTEASELFKSEEGYHLTVLFSIEDEEPIRAKQLQAHLLEYGEPAQH
TRAYLLEHAVKLLDHTAVDKLKTIELV

Nucleotide


Download         Length: 804 bp        

>NTDB_id=1067655 ACFSN5_RS01080 WP_165211838.1 204561..205364(+) (mecA) [Streptococcus sp. ZJ 1593]
ATGGAAATGAAACAAATTAATGAGTCGACACTCAAGATTTCTGTTAGTCTTGAAGATCTTGATTCATACGGCATGGAACT
AAAAGATTTCCTGATGCCTCAAGAAAAAACAGAAGAATTTTTCTATACTATTTTAGATGAATTGGATATCCCAGATAGTT
TTAAATCAACTGGTATGTTAAGCTTCCGGGTAACTCCCCGTAAAGATCGGGTCGATGTTTTTGTAACAAAGTCTGAGCTT
AATGAAAGTCTGGATTTTGAACAGTTAGCCGAAGATATGGGGGATATGTCAGACATGAATCCAGAGGATTTTTTCAAAAA
TCTGGAAAAGAATATGATGGCCCAGGGTGATACTGAAGCTCATGAAAAATTGAAAAATTTGGAAGCCATGCTAGATGATG
CTATCGGTGATTTGCCAGAAGAAGTTCAAGCAGTAACAACTGGTTCAGAAGACGGTGAGAGCGATGCTAGGGCTTTCAGG
CTTAAAGAGGAGGATTTAATTCCTGTTACCAGTTATGCGCATTATGTTGCAGACTTTCCTAATTTGGAAGCCGTTATTGT
AGCAGCCAAGGCCTTGGCTGTGCCAACTGAGGCTTCAGAACTCTTTAAATCAGAAGAAGGCTATCATTTGACAGTTCTCT
TTAGCATTGAAGATGAAGAACCTATTCGCGCTAAGCAGCTGCAAGCTCATCTTTTAGAATATGGTGAACCTGCTCAGCAC
ACCCGAGCCTATCTCTTGGAGCATGCTGTTAAACTTTTGGATCATACAGCAGTAGATAAATTGAAAACGATAGAATTGGT
ATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

48.864

98.876

0.483
  mecA Streptococcus thermophilus LMG 18311

47.909

98.502

0.472
  mecA Streptococcus thermophilus LMD-9

47.529

98.502

0.468
  mecA Streptococcus pneumoniae Rx1

41.353

99.625

0.412
  mecA Streptococcus pneumoniae D39

41.353

99.625

0.412
  mecA Streptococcus pneumoniae R6

41.353

99.625

0.412
  mecA Streptococcus pneumoniae TIGR4

41.353

99.625

0.412

Multiple sequence alignment