Detailed information NTG0106570

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: AABJ45_RS02555
• Genome accession: NZ_AP028611
• Coordinates: 512176..512913 (+)
• Length: 245 a.a.
• NCBI ID: WP_001219119.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep6
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 507176..517913

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABJ45_RS02520 (TKY121527_05000)	-	508151..508345 (-)	195	WP_001827223.1	hypothetical protein	-
AABJ45_RS02525 (TKY121527_05010)	-	508507..508794 (-)	288	WP_000777753.1	hypothetical protein	-
AABJ45_RS02530 (TKY121527_05020)	-	508804..509214 (-)	411	WP_001278301.1	HIT family protein	-
AABJ45_RS02535 (TKY121527_05030)	pptA	509282..510013 (+)	732	WP_000889921.1	ABC transporter ATP-binding protein	Regulator
AABJ45_RS02540 (TKY121527_05040)	-	510010..511059 (+)	1050	WP_338372279.1	ABC transporter permease	-
AABJ45_RS02545 (TKY121527_05050)	-	511227..511556 (-)	330	WP_000132572.1	hypothetical protein	-
AABJ45_RS02550 (TKY121527_05060)	-	511833..512171 (+)	339	WP_000876675.1	LytTR family DNA-binding domain-containing protein	-
AABJ45_RS02555 (TKY121527_05070)	comE/blpR	512176..512913 (+)	738	WP_001219119.1	LytTR family DNA-binding domain-containing protein	Regulator
AABJ45_RS02560 (TKY121527_05090)	-	512927..514256 (+)	1330	Protein_503	sensor histidine kinase	-
AABJ45_RS02565 (TKY121527_05100)	blpC	514300..514455 (-)	156	WP_000358811.1	quorum-sensing system pheromone BlpC	-
AABJ45_RS02570 (TKY121527_05110)	-	514512..515873 (-)	1362	WP_001069103.1	bacteriocin secretion accessory protein	-
AABJ45_RS02575 (TKY121527_05120)	comA/nlmT	515884..516795 (-)	912	WP_001827226.1	ATP-binding cassette domain-containing protein	Regulator
AABJ45_RS02580 (TKY121527_05130)	comA/nlmT	516785..517510 (-)	726	WP_167750760.1	ABC transporter transmembrane domain-containing protein	Regulator

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28706.89 Da
• Isoelectric Point: 6.4140

>NTDB_id=106570 AABJ45_RS02555 WP_001219119.1 512176..512913(+) (comE/blpR) [Streptococcus pneumoniae strain Sep6]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide

• Length: 738 bp

>NTDB_id=106570 AABJ45_RS02555 WP_001219119.1 512176..512913(+) (comE/blpR) [Streptococcus pneumoniae strain Sep6]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAAGAGATGAAGGGACTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-122)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.036	100	0.535
comE/comE1	Streptococcus equinus JB1	43.038	96.735	0.416
comE/comE2	Streptococcus equinus JB1	38.43	98.776	0.38